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A polyamine-centric, blood-based metabolite panel predictive of poor response to CAR-T cell therapy in large B cell lymphoma.
Fahrmann JF, Saini NY, Chia-Chi C, Irajizad E, Strati P, Nair R, Fayad LE, Ahmed S, Lee HJ, Iyer S, Steiner R, Vykoukal J, Wu R, Dennison JB, Nastoupil L, Jain P, Wang M, Green M, Westin J, Blumenberg V, Davila M, Champlin R, Shpall EJ, Kebriaei P, Flowers CR, Jain M, Jenq R, Stein-Thoeringer CK, Subklewe M, Neelapu SS, Hanash S. Fahrmann JF, et al. Cell Rep Med. 2022 Nov 15;3(11):100720. doi: 10.1016/j.xcrm.2022.100720. Cell Rep Med. 2022. PMID: 36384092 Free PMC article.
A blood-based metabolomic signature predictive of risk for pancreatic cancer.
Irajizad E, Kenney A, Tang T, Vykoukal J, Wu R, Murage E, Dennison JB, Sans M, Long JP, Loftus M, Chabot JA, Kluger MD, Kastrinos F, Brais L, Babic A, Jajoo K, Lee LS, Clancy TE, Ng K, Bullock A, Genkinger JM, Maitra A, Do KA, Yu B, Wolpin BM, Hanash S, Fahrmann JF. Irajizad E, et al. Among authors: fahrmann jf. Cell Rep Med. 2023 Sep 19;4(9):101194. doi: 10.1016/j.xcrm.2023.101194. Cell Rep Med. 2023. PMID: 37729870 Free PMC article.
Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential.
Sans M, Makino Y, Min J, Rajapakshe KI, Yip-Schneider M, Schmidt CM, Hurd MW, Burks JK, Gomez JA, Thege FI, Fahrmann JF, Wolff RA, Kim MP, Guerrero PA, Maitra A. Sans M, et al. Among authors: fahrmann jf. Cancer Discov. 2023 Aug 4;13(8):1844-1861. doi: 10.1158/2159-8290.CD-22-1200. Cancer Discov. 2023. PMID: 37285225 Free PMC article.
Kynureninase Upregulation Is a Prominent Feature of NFR2-Activated Cancers and Is Associated with Tumor Immunosuppression and Poor Prognosis.
León-Letelier RA, Abdel Sater AH, Chen Y, Park S, Wu R, Irajizad E, Dennison JB, Katayama H, Vykoukal JV, Hanash S, Ostrin EJ, Fahrmann JF. León-Letelier RA, et al. Among authors: fahrmann jf. Cancers (Basel). 2023 Jan 29;15(3):834. doi: 10.3390/cancers15030834. Cancers (Basel). 2023. PMID: 36765792 Free PMC article.
Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites: insights from the BE GONE trial.
Zhang X, Irajizad E, Hoffman KL, Fahrmann JF, Li F, Seo YD, Browman GJ, Dennison JB, Vykoukal J, Luna PN, Siu W, Wu R, Murage E, Ajami NJ, McQuade JL, Wargo JA, Long JP, Do KA, Lampe JW, Basen-Engquist KM, Okhuysen PC, Kopetz S, Hanash SM, Petrosino JF, Scheet P, Daniel CR. Zhang X, et al. Among authors: fahrmann jf. EBioMedicine. 2023 Dec;98:104873. doi: 10.1016/j.ebiom.2023.104873. Epub 2023 Nov 30. EBioMedicine. 2023. PMID: 38040541 Free PMC article. Clinical Trial.
Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma.
Wikoff WR, Grapov D, Fahrmann JF, DeFelice B, Rom WN, Pass HI, Kim K, Nguyen U, Taylor SL, Gandara DR, Kelly K, Fiehn O, Miyamoto S. Wikoff WR, et al. Among authors: fahrmann jf. Cancer Prev Res (Phila). 2015 May;8(5):410-8. doi: 10.1158/1940-6207.CAPR-14-0329. Epub 2015 Feb 5. Cancer Prev Res (Phila). 2015. PMID: 25657018 Free PMC article.
Diabetes Associated Metabolomic Perturbations in NOD Mice.
Grapov D, Fahrmann J, Hwang J, Poudel A, Jo J, Periwal V, Fiehn O, Hara M. Grapov D, et al. Metabolomics. 2015 Apr;11(2):425-437. doi: 10.1007/s11306-014-0706-2. Metabolomics. 2015. PMID: 25755629 Free PMC article.
87 results