Heerspink HJL - Search Results

1

A metabolomics-based molecular pathway analysis of how the sodium-glucose co-transporter-2 inhibitor dapagliflozin may slow kidney function decline in patients with diabetes.

Mulder S, Hammarstedt A, Nagaraj SB, Nair V, Ju W, Hedberg J, Greasley PJ, Eriksson JW, Oscarsson J, Heerspink HJL. Mulder S, et al. Among authors: heerspink hjl. Diabetes Obes Metab. 2020 Jul;22(7):1157-1166. doi: 10.1111/dom.14018. Epub 2020 Mar 25. Diabetes Obes Metab. 2020. PMID: 32115853 Free PMC article. Clinical Trial.

2

Is a reduction in albuminuria associated with renal and cardiovascular protection? A post hoc analysis of the ALTITUDE trial.

Heerspink HJ, Ninomiya T, Persson F, Brenner BM, Brunel P, Chaturvedi N, Desai AS, Haffner SM, Mcmurray JJ, Solomon SD, Pfeffer MA, Parving HH, de Zeeuw D. Heerspink HJ, et al. Diabetes Obes Metab. 2016 Feb;18(2):169-77. doi: 10.1111/dom.12600. Epub 2016 Jan 13. Diabetes Obes Metab. 2016. PMID: 26511599 Clinical Trial.

3

Dapagliflozin reduces albuminuria in patients with diabetes and hypertension receiving renin-angiotensin blockers.

Heerspink HJ, Johnsson E, Gause-Nilsson I, Cain VA, Sjöström CD. Heerspink HJ, et al. Diabetes Obes Metab. 2016 Jun;18(6):590-7. doi: 10.1111/dom.12654. Diabetes Obes Metab. 2016. PMID: 26936519 Free PMC article. Clinical Trial.

4

Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus: Cardiovascular and Kidney Effects, Potential Mechanisms, and Clinical Applications.

Heerspink HJ, Perkins BA, Fitchett DH, Husain M, Cherney DZ. Heerspink HJ, et al. Circulation. 2016 Sep 6;134(10):752-72. doi: 10.1161/CIRCULATIONAHA.116.021887. Epub 2016 Jul 28. Circulation. 2016. PMID: 27470878 Review.

5

Canagliflozin Slows Progression of Renal Function Decline Independently of Glycemic Effects.

Heerspink HJ, Desai M, Jardine M, Balis D, Meininger G, Perkovic V. Heerspink HJ, et al. J Am Soc Nephrol. 2017 Jan;28(1):368-375. doi: 10.1681/ASN.2016030278. Epub 2016 Aug 18. J Am Soc Nephrol. 2017. PMID: 27539604 Free PMC article. Clinical Trial.

6

Comparison of exposure response relationship of atrasentan between North American and Asian populations.

Heerspink HJ, Makino H, Andress D, Brennan JJ, Correa-Rotter R, Coll B, Davis JW, Idler K, Kohan DE, Liu M, Perkovic V, Remuzzi G, Tobe SW, Toto R, Parving HH, de Zeeuw D. Heerspink HJ, et al. Diabetes Obes Metab. 2017 Apr;19(4):545-552. doi: 10.1111/dom.12851. Epub 2017 Jan 27. Diabetes Obes Metab. 2017. PMID: 27981738 Clinical Trial.

7

The effects of atrasentan on urinary metabolites in patients with type 2 diabetes and nephropathy.

Pena MJ, de Zeeuw D, Andress D, Brennan JJ, Correa-Rotter R, Coll B, Kohan DE, Makino H, Perkovic V, Remuzzi G, Tobe SW, Toto R, Parving HH, Sharma S, Corringham T, Sharma K, Heerspink HJL. Pena MJ, et al. Among authors: heerspink hjl. Diabetes Obes Metab. 2017 May;19(5):749-753. doi: 10.1111/dom.12864. Epub 2017 Feb 22. Diabetes Obes Metab. 2017. PMID: 28019071 Clinical Trial.

8

Systems Biology-Derived Biomarkers to Predict Progression of Renal Function Decline in Type 2 Diabetes.

Mayer G, Heerspink HJ, Aschauer C, Heinzel A, Heinze G, Kainz A, Sunzenauer J, Perco P, de Zeeuw D, Rossing P, Pena M, Oberbauer R; SYSKID Consortium. Mayer G, et al. Diabetes Care. 2017 Mar;40(3):391-397. doi: 10.2337/dc16-2202. Epub 2017 Jan 11. Diabetes Care. 2017. PMID: 28077457

9

Effect of linagliptin on pulse wave velocity in early type 2 diabetes: A randomized, double-blind, controlled 26-week trial (RELEASE).

de Boer SA, Heerspink HJL, Juárez Orozco LE, van Roon AM, Kamphuisen PW, Smit AJ, Slart RHJA, Lefrandt JD, Mulder DJ. de Boer SA, et al. Among authors: heerspink hjl. Diabetes Obes Metab. 2017 Aug;19(8):1147-1154. doi: 10.1111/dom.12925. Epub 2017 Apr 10. Diabetes Obes Metab. 2017. PMID: 28244635 Clinical Trial.

10

The albuminuria-lowering response to dapagliflozin is variable and reproducible among individual patients.

Petrykiv SI, Laverman GD, de Zeeuw D, Heerspink HJL. Petrykiv SI, et al. Among authors: heerspink hjl. Diabetes Obes Metab. 2017 Oct;19(10):1363-1370. doi: 10.1111/dom.12936. Epub 2017 Jun 8. Diabetes Obes Metab. 2017. PMID: 28295959 Clinical Trial.

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