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Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma.
J Med Chem. 2020 Jul 9;63(13):6648-6676. doi: 10.1021/acs.jmedchem.9b01928. Epub 2020 Mar 19.
J Med Chem. 2020.
PMID: 32130004
Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor.
Teng M, Johnson MD, Thomas C, Kiel D, Lakis JN, Kercher T, Aytes S, Kostrowicki J, Bhumralkar D, Truesdale L, May J, Sidelman U, Kodra JT, Jørgensen AS, Olesen PH, de Jong JC, Madsen P, Behrens C, Pettersson I, Knudsen LB, Holst JJ, Lau J.
Teng M, et al. Among authors: kercher t.
Bioorg Med Chem Lett. 2007 Oct 1;17(19):5472-8. doi: 10.1016/j.bmcl.2007.06.086. Epub 2007 Jul 4.
Bioorg Med Chem Lett. 2007.
PMID: 17827014
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Small-molecule agonists for the glucagon-like peptide 1 receptor.
Knudsen LB, Kiel D, Teng M, Behrens C, Bhumralkar D, Kodra JT, Holst JJ, Jeppesen CB, Johnson MD, de Jong JC, Jorgensen AS, Kercher T, Kostrowicki J, Madsen P, Olesen PH, Petersen JS, Poulsen F, Sidelmann UG, Sturis J, Truesdale L, May J, Lau J.
Knudsen LB, et al. Among authors: kercher t.
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):937-42. doi: 10.1073/pnas.0605701104. Epub 2007 Jan 9.
Proc Natl Acad Sci U S A. 2007.
PMID: 17213325
Free PMC article.
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Diversification of the three-component coupling of 2-aminoheterocycles, aldehydes, and isonitriles: efficient parallel synthesis of a diverse and druglike library of imidazo- and tetrahydroimidazo[1,2-a] heterocycles.
Kercher T, Rao C, Bencsik JR, Josey JA.
Kercher T, et al.
J Comb Chem. 2007 Nov-Dec;9(6):1177-87. doi: 10.1021/cc0700290. Epub 2007 Sep 8.
J Comb Chem. 2007.
PMID: 17824665
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Glyoxylic acid and MP-glyoxylate: efficient formaldehyde equivalents in the 3-CC of 2-aminoazines, aldehydes, and isonitriles.
Lyon MA, Kercher TS.
Lyon MA, et al. Among authors: kercher ts.
Org Lett. 2004 Dec 23;6(26):4989-92. doi: 10.1021/ol0478234.
Org Lett. 2004.
PMID: 15606117
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Efficient, stereoselective synthesis of oxazolo[3,2-a]pyrazin-5-ones: novel bicyclic lactam scaffolds from the bicyclocondensation of 3-aza-1,5-ketoacids and amino alcohols.
Bencsik JR, Kercher T, O'Sullivan M, Josey JA.
Bencsik JR, et al. Among authors: kercher t.
Org Lett. 2003 Jul 24;5(15):2727-30. doi: 10.1021/ol030065h.
Org Lett. 2003.
PMID: 12868900
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