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Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition.
Gorini G, Fourati S, Vaccari M, Rahman MA, Gordon SN, Brown DR, Law L, Chang J, Green R, Barrenäs F, Liyanage NPM, Doster MN, Schifanella L, Bissa M, Silva de Castro I, Washington-Parks R, Galli V, Fuller DH, Santra S, Agy M, Pal R, Palermo RE, Tomaras GD, Shen X, LaBranche CC, Montefiori DC, Venzon DJ, Trinh HV, Rao M, Gale M Jr, Sekaly RP, Franchini G. Gorini G, et al. Among authors: tomaras gd. PLoS Pathog. 2020 Mar 12;16(3):e1008377. doi: 10.1371/journal.ppat.1008377. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32163525 Free PMC article.
In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth.
Shen X, Parks RJ, Montefiori DC, Kirchherr JL, Keele BF, Decker JM, Blattner WA, Gao F, Weinhold KJ, Hicks CB, Greenberg ML, Hahn BH, Shaw GM, Haynes BF, Tomaras GD. Shen X, et al. Among authors: tomaras gd. J Virol. 2009 Apr;83(8):3617-25. doi: 10.1128/JVI.02631-08. Epub 2009 Feb 4. J Virol. 2009. PMID: 19193787 Free PMC article.
Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution.
Shen X, Dennison SM, Liu P, Gao F, Jaeger F, Montefiori DC, Verkoczy L, Haynes BF, Alam SM, Tomaras GD. Shen X, et al. Among authors: tomaras gd. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5972-7. doi: 10.1073/pnas.0912381107. Epub 2010 Mar 15. Proc Natl Acad Sci U S A. 2010. PMID: 20231447 Free PMC article.
Alterations of the B-cell response by HIV-1 replication.
Shen X, Tomaras GD. Shen X, et al. Among authors: tomaras gd. Curr HIV/AIDS Rep. 2011 Mar;8(1):23-30. doi: 10.1007/s11904-010-0064-2. Curr HIV/AIDS Rep. 2011. PMID: 21161615 Free PMC article.
HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies.
Fouda GG, Yates NL, Pollara J, Shen X, Overman GR, Mahlokozera T, Wilks AB, Kang HH, Salazar-Gonzalez JF, Salazar MG, Kalilani L, Meshnick SR, Hahn BH, Shaw GM, Lovingood RV, Denny TN, Haynes B, Letvin NL, Ferrari G, Montefiori DC, Tomaras GD, Permar SR; Center for HIV/AIDS Vaccine Immunology. Fouda GG, et al. Among authors: tomaras gd. J Virol. 2011 Sep;85(18):9555-67. doi: 10.1128/JVI.05174-11. Epub 2011 Jul 6. J Virol. 2011. PMID: 21734046 Free PMC article.
High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses.
Pollara J, Hart L, Brewer F, Pickeral J, Packard BZ, Hoxie JA, Komoriya A, Ochsenbauer C, Kappes JC, Roederer M, Huang Y, Weinhold KJ, Tomaras GD, Haynes BF, Montefiori DC, Ferrari G. Pollara J, et al. Among authors: tomaras gd. Cytometry A. 2011 Aug;79(8):603-12. doi: 10.1002/cyto.a.21084. Epub 2011 Jul 6. Cytometry A. 2011. PMID: 21735545 Free PMC article.
Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals.
Tomaras GD, Binley JM, Gray ES, Crooks ET, Osawa K, Moore PL, Tumba N, Tong T, Shen X, Yates NL, Decker J, Wibmer CK, Gao F, Alam SM, Easterbrook P, Abdool Karim S, Kamanga G, Crump JA, Cohen M, Shaw GM, Mascola JR, Haynes BF, Montefiori DC, Morris L. Tomaras GD, et al. J Virol. 2011 Nov;85(21):11502-19. doi: 10.1128/JVI.05363-11. Epub 2011 Aug 17. J Virol. 2011. PMID: 21849452 Free PMC article.
Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies.
Ma BJ, Alam SM, Go EP, Lu X, Desaire H, Tomaras GD, Bowman C, Sutherland LL, Scearce RM, Santra S, Letvin NL, Kepler TB, Liao HX, Haynes BF. Ma BJ, et al. Among authors: tomaras gd. PLoS Pathog. 2011 Sep;7(9):e1002200. doi: 10.1371/journal.ppat.1002200. Epub 2011 Sep 1. PLoS Pathog. 2011. PMID: 21909262 Free PMC article.
Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41.
Dennison SM, Sutherland LL, Jaeger FH, Anasti KM, Parks R, Stewart S, Bowman C, Xia SM, Zhang R, Shen X, Scearce RM, Ofek G, Yang Y, Kwong PD, Santra S, Liao HX, Tomaras G, Letvin NL, Chen B, Alam SM, Haynes BF. Dennison SM, et al. PLoS One. 2011;6(11):e27824. doi: 10.1371/journal.pone.0027824. Epub 2011 Nov 30. PLoS One. 2011. PMID: 22140469 Free PMC article.
369 results