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Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity.
Kavazović I, Han H, Balzaretti G, Slinger E, Lemmermann NAW, Ten Brinke A, Merkler D, Koster J, Bryceson YT, de Vries N, Jonjić S, Klarenbeek PL, Polić B, Eldering E, Wensveen FM. Kavazović I, et al. Among authors: bryceson yt. PLoS Biol. 2020 Mar 17;18(3):e3000648. doi: 10.1371/journal.pbio.3000648. eCollection 2020 Mar. PLoS Biol. 2020. PMID: 32182234 Free PMC article.
Natural killer cell memory in context.
Holmes TD, Bryceson YT. Holmes TD, et al. Among authors: bryceson yt. Semin Immunol. 2016 Aug;28(4):368-76. doi: 10.1016/j.smim.2016.05.008. Epub 2016 Jun 25. Semin Immunol. 2016. PMID: 27354353 Review.
Hobit identifies tissue-resident memory T cell precursors that are regulated by Eomes.
Parga-Vidal L, Behr FM, Kragten NAM, Nota B, Wesselink TH, Kavazović I, Covill LE, Schuller MBP, Bryceson YT, Wensveen FM, van Lier RAW, van Dam TJP, Stark R, van Gisbergen KPJM. Parga-Vidal L, et al. Among authors: bryceson yt. Sci Immunol. 2021 Aug 20;6(62):eabg3533. doi: 10.1126/sciimmunol.abg3533. Sci Immunol. 2021. PMID: 34417257
Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function.
Schlums H, Cichocki F, Tesi B, Theorell J, Beziat V, Holmes TD, Han H, Chiang SC, Foley B, Mattsson K, Larsson S, Schaffer M, Malmberg KJ, Ljunggren HG, Miller JS, Bryceson YT. Schlums H, et al. Among authors: bryceson yt. Immunity. 2015 Mar 17;42(3):443-56. doi: 10.1016/j.immuni.2015.02.008. Immunity. 2015. PMID: 25786176 Free PMC article.
Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells.
Schlums H, Jung M, Han H, Theorell J, Bigley V, Chiang SC, Allan DS, Davidson-Moncada JK, Dickinson RE, Holmes TD, Hsu AP, Townsley D, Winkler T, Wang W, Aukrust P, Nordøy I, Calvo KR, Holland SM, Collin M, Dunbar CE, Bryceson YT. Schlums H, et al. Among authors: bryceson yt. Blood. 2017 Apr 6;129(14):1927-1939. doi: 10.1182/blood-2016-08-734236. Epub 2017 Feb 16. Blood. 2017. PMID: 28209719 Free PMC article.
CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin.
Cheuk S, Schlums H, Gallais Sérézal I, Martini E, Chiang SC, Marquardt N, Gibbs A, Detlofsson E, Introini A, Forkel M, Höög C, Tjernlund A, Michaëlsson J, Folkersen L, Mjösberg J, Blomqvist L, Ehrström M, Ståhle M, Bryceson YT, Eidsmo L. Cheuk S, et al. Among authors: bryceson yt. Immunity. 2017 Feb 21;46(2):287-300. doi: 10.1016/j.immuni.2017.01.009. Epub 2017 Feb 14. Immunity. 2017. PMID: 28214226 Free PMC article.
Patients with both Langerhans cell histiocytosis and Crohn's disease highlight a common role of interleukin-23.
Kvedaraite E, Lourda M, Han H, Tesi B, Mitchell J, Ideström M, Mouratidou N, Rassidakis G, von Bahr Greenwood T, Cohen-Aubart F, Jädersten M, Åkefeldt SO, Svensson M, Kannourakis G, Bryceson YT, Haroche J, Henter JI. Kvedaraite E, et al. Among authors: bryceson yt. Acta Paediatr. 2021 Apr;110(4):1315-1321. doi: 10.1111/apa.15590. Epub 2020 Oct 8. Acta Paediatr. 2021. PMID: 32975844 Free PMC article.
The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation.
Holmes TD, Pandey RV, Helm EY, Schlums H, Han H, Campbell TM, Drashansky TT, Chiang S, Wu CY, Tao C, Shoukier M, Tolosa E, Von Hardenberg S, Sun M, Klemann C, Marsh RA, Lau CM, Lin Y, Sun JC, Månsson R, Cichocki F, Avram D, Bryceson YT. Holmes TD, et al. Among authors: bryceson yt. Sci Immunol. 2021 Mar 12;6(57):eabc9801. doi: 10.1126/sciimmunol.abc9801. Sci Immunol. 2021. PMID: 33712472 Free PMC article.
Bcl11b sustains multipotency and restricts effector programs of intestinal-resident memory CD8+ T cells.
Helm EY, Zelenka T, Cismasiu VB, Islam S, Silvane L, Zitti B, Holmes TD, Drashansky TT, Kwiatkowski AJ, Tao C, Dean J, Obermayer AN, Chen X, Keselowsky BG, Zhang W, Huo Z, Zhou L, Sheridan BS, Conejo-Garcia JR, Shaw TI, Bryceson YT, Avram D. Helm EY, et al. Among authors: bryceson yt. Sci Immunol. 2023 Apr 28;8(82):eabn0484. doi: 10.1126/sciimmunol.abn0484. Epub 2023 Apr 28. Sci Immunol. 2023. PMID: 37115913 Free PMC article.
170 results