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Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis.
Moreira-Teixeira L, Tabone O, Graham CM, Singhania A, Stavropoulos E, Redford PS, Chakravarty P, Priestnall SL, Suarez-Bonnet A, Herbert E, Mayer-Barber KD, Sher A, Fonseca KL, Sousa J, Cá B, Verma R, Haldar P, Saraiva M, O'Garra A. Moreira-Teixeira L, et al. Among authors: singhania a. Nat Immunol. 2020 Apr;21(4):464-476. doi: 10.1038/s41590-020-0610-z. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205882 Free PMC article.
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.
Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, Frickel E, Sesay AK, Priestnall SL, Herbert E, Ioannou M, Wang Q, Humphreys IR, Dodd J, Openshaw PJM, Mayer-Barber KD, Jankovic D, Sher A, Lloyd CM, Baldwin N, Chaussabel D, Papayannopoulos V, Wack A, Banchereau JF, Pascual VM, O'Garra A. Singhania A, et al. Nat Commun. 2019 Jun 28;10(1):2887. doi: 10.1038/s41467-019-10601-6. Nat Commun. 2019. PMID: 31253760 Free PMC article.
Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosis.
Hillman H, Khan N, Singhania A, Dubelko P, Soldevila F, Tippalagama R, DeSilva AD, Gunasena B, Perera J, Scriba TJ, Ontong C, Fisher M, Luabeya A, Taplitz R, Seumois G, Vijayanand P, Hedrick CC, Peters B, Burel JG. Hillman H, et al. Among authors: singhania a. Front Immunol. 2023 Jan 11;13:1087010. doi: 10.3389/fimmu.2022.1087010. eCollection 2022. Front Immunol. 2023. PMID: 36713384 Free PMC article.
Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection.
Chancellor A, White A, Tocheva AS, Fenn JR, Dennis M, Tezera L, Singhania A, Elliott T, Tebruegge M, Elkington P, Gadola S, Sharpe S, Mansour S. Chancellor A, et al. Among authors: singhania a. Tuberculosis (Edinb). 2017 Jul;105:86-95. doi: 10.1016/j.tube.2017.04.011. Epub 2017 Apr 28. Tuberculosis (Edinb). 2017. PMID: 28610792 Free PMC article.
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.
Jevnikar Z, Östling J, Ax E, Calvén J, Thörn K, Israelsson E, Öberg L, Singhania A, Lau LCK, Wilson SJ, Ward JA, Chauhan A, Sousa AR, De Meulder B, Loza MJ, Baribaud F, Sterk PJ, Chung KF, Sun K, Guo Y, Adcock IM, Payne D, Dahlen B, Chanez P, Shaw DE, Krug N, Hohlfeld JM, Sandström T, Djukanovic R, James A, Hinks TSC, Howarth PH, Vaarala O, van Geest M, Olsson H; Unbiased Biomarkers in Prediction of Respiratory Disease Outcomes study group. Jevnikar Z, et al. Among authors: singhania a. J Allergy Clin Immunol. 2019 Feb;143(2):577-590. doi: 10.1016/j.jaci.2018.05.026. Epub 2018 Jun 11. J Allergy Clin Immunol. 2019. PMID: 29902480 Free article.
HLA-DR Marks Recently Divided Antigen-Specific Effector CD4 T Cells in Active Tuberculosis Patients.
Tippalagama R, Singhania A, Dubelko P, Lindestam Arlehamn CS, Crinklaw A, Pomaznoy M, Seumois G, deSilva AD, Premawansa S, Vidanagama D, Gunasena B, Goonawardhana NDS, Ariyaratne D, Scriba TJ, Gilman RH, Saito M, Taplitz R, Vijayanand P, Sette A, Peters B, Burel JG. Tippalagama R, et al. Among authors: singhania a. J Immunol. 2021 Jul 15;207(2):523-533. doi: 10.4049/jimmunol.2100011. Epub 2021 Jun 30. J Immunol. 2021. PMID: 34193602 Free PMC article.
Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease.
Burel JG, Singhania A, Dubelko P, Muller J, Tanner R, Parizotto E, Dedicoat M, Fletcher TE, Dunbar J, Cunningham AF, Lindestam Arlehamn CS, Catanzaro DG, Catanzaro A, Rodwell T, McShane H, O'Shea MK, Peters B. Burel JG, et al. Among authors: singhania a. Tuberculosis (Edinb). 2021 Dec;131:102127. doi: 10.1016/j.tube.2021.102127. Epub 2021 Sep 14. Tuberculosis (Edinb). 2021. PMID: 34555657 Free PMC article.
77 results