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Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease.
Mayr L, Grabherr F, Schwärzler J, Reitmeier I, Sommer F, Gehmacher T, Niederreiter L, He GW, Ruder B, Kunz KTR, Tymoszuk P, Hilbe R, Haschka D, Feistritzer C, Gerner RR, Enrich B, Przysiecki N, Seifert M, Keller MA, Oberhuber G, Sprung S, Ran Q, Koch R, Effenberger M, Tancevski I, Zoller H, Moschen AR, Weiss G, Becker C, Rosenstiel P, Kaser A, Tilg H, Adolph TE. Mayr L, et al. Among authors: he gw. Nat Commun. 2020 Apr 14;11(1):1775. doi: 10.1038/s41467-020-15646-6. Nat Commun. 2020. PMID: 32286299 Free PMC article.
Interferon Lambda Promotes Paneth Cell Death Via STAT1 Signaling in Mice and Is Increased in Inflamed Ileal Tissues of Patients With Crohn's Disease.
Günther C, Ruder B, Stolzer I, Dorner H, He GW, Chiriac MT, Aden K, Strigli A, Bittel M, Zeissig S, Rosenstiel P, Atreya R, Neurath MF, Wirtz S, Becker C. Günther C, et al. Among authors: he gw. Gastroenterology. 2019 Nov;157(5):1310-1322.e13. doi: 10.1053/j.gastro.2019.07.031. Epub 2019 Jul 25. Gastroenterology. 2019. PMID: 31352002
PGAM5 is a key driver of mitochondrial dysfunction in experimental lung fibrosis.
Ganzleben I, He GW, Günther C, Prigge ES, Richter K, Rieker RJ, Mougiakakos D, Neurath MF, Becker C. Ganzleben I, et al. Among authors: he gw. Cell Mol Life Sci. 2019 Dec;76(23):4783-4794. doi: 10.1007/s00018-019-03133-1. Epub 2019 Jun 5. Cell Mol Life Sci. 2019. PMID: 31168659 Free PMC article.
Wheat Consumption Aggravates Colitis in Mice via Amylase Trypsin Inhibitor-mediated Dysbiosis.
Pickert G, Wirtz S, Matzner J, Ashfaq-Khan M, Heck R, Rosigkeit S, Thies D, Surabattula R, Ehmann D, Wehkamp J, Aslam M, He G, Weigert A, Foerster F, Klotz L, Frick JS, Becker C, Bockamp E, Schuppan D. Pickert G, et al. Gastroenterology. 2020 Jul;159(1):257-272.e17. doi: 10.1053/j.gastro.2020.03.064. Epub 2020 Apr 3. Gastroenterology. 2020. PMID: 32251667
Programming of Intestinal Epithelial Differentiation by IL-33 Derived from Pericryptal Fibroblasts in Response to Systemic Infection.
Mahapatro M, Foersch S, Hefele M, He GW, Giner-Ventura E, Mchedlidze T, Kindermann M, Vetrano S, Danese S, Günther C, Neurath MF, Wirtz S, Becker C. Mahapatro M, et al. Among authors: he gw. Cell Rep. 2016 May 24;15(8):1743-56. doi: 10.1016/j.celrep.2016.04.049. Epub 2016 May 12. Cell Rep. 2016. PMID: 27184849 Free article.
307 results