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CD4/CD8 T-Cell Selection Affects Chimeric Antigen Receptor (CAR) T-Cell Potency and Toxicity: Updated Results From a Phase I Anti-CD22 CAR T-Cell Trial.
Shah NN, Highfill SL, Shalabi H, Yates B, Jin J, Wolters PL, Ombrello A, Steinberg SM, Martin S, Delbrook C, Hoffman L, Little L, Ponduri A, Qin H, Qureshi H, Dulau-Florea A, Salem D, Wang HW, Yuan C, Stetler-Stevenson M, Panch S, Tran M, Mackall CL, Stroncek DF, Fry TJ. Shah NN, et al. Among authors: highfill sl. J Clin Oncol. 2020 Jun 10;38(17):1938-1950. doi: 10.1200/JCO.19.03279. Epub 2020 Apr 14. J Clin Oncol. 2020. PMID: 32286905 Free PMC article. Clinical Trial.
Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity.
Lundström W, Highfill S, Walsh ST, Beq S, Morse E, Kockum I, Alfredsson L, Olsson T, Hillert J, Mackall CL. Lundström W, et al. Proc Natl Acad Sci U S A. 2013 May 7;110(19):E1761-70. doi: 10.1073/pnas.1222303110. Epub 2013 Apr 22. Proc Natl Acad Sci U S A. 2013. PMID: 23610432 Free PMC article.
A pan-inhibitor of DASH family enzymes induces immune-mediated regression of murine sarcoma and is a potent adjuvant to dendritic cell vaccination and adoptive T-cell therapy.
Duncan BB, Highfill SL, Qin H, Bouchkouj N, Larabee S, Zhao P, Woznica I, Liu Y, Li Y, Wu W, Lai JH, Jones B, Mackall CL, Bachovchin WW, Fry TJ. Duncan BB, et al. Among authors: highfill sl. J Immunother. 2013 Oct;36(8):400-11. doi: 10.1097/CJI.0b013e3182a80213. J Immunother. 2013. PMID: 23994886 Free PMC article.
A Phase 1 trial of autologous monocytes stimulated ex vivo with Sylatron® (Peginterferon alfa-2b) and Actimmune® (Interferon gamma-1b) for intra-peritoneal administration in recurrent ovarian cancer.
Green DS, Nunes AT, David-Ocampo V, Ekwede IB, Houston ND, Highfill SL, Khuu H, Stroncek DF, Steinberg SM, Zoon KC, Annunziata CM. Green DS, et al. Among authors: highfill sl. J Transl Med. 2018 Jul 16;16(1):196. doi: 10.1186/s12967-018-1569-5. J Transl Med. 2018. PMID: 30012146 Free PMC article. Clinical Trial.
60 results