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Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.
Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. Hsiao F, et al. Among authors: roychoudhury p. PLoS Pathog. 2020 Apr 30;16(4):e1008450. doi: 10.1371/journal.ppat.1008450. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32353080 Free PMC article.
A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir.
Levy CN, Hughes SM, Roychoudhury P, Reeves DB, Amstuz C, Zhu H, Huang ML, Wei Y, Bull ME, Cassidy NAJ, McClure J, Frenkel LM, Stone M, Bakkour S, Wonderlich ER, Busch MP, Deeks SG, Schiffer JT, Coombs RW, Lehman DA, Jerome KR, Hladik F. Levy CN, et al. Among authors: roychoudhury p. Cell Rep Med. 2021 Apr 12;2(4):100243. doi: 10.1016/j.xcrm.2021.100243. eCollection 2021 Apr 20. Cell Rep Med. 2021. PMID: 33948574 Free PMC article.
Host variation in type I interferon signaling genes (MX1), C-C chemokine receptor type 5 gene, and major histocompatibility complex class I alleles in treated HIV+ noncontrollers predict viral reservoir size.
Siegel DA, Thanh C, Wan E, Hoh R, Hobbs K, Pan T, Gibson EA, Kroetz DL, Martin J, Hecht F, Pilcher C, Martin M, Carrington M, Pillai S, Busch MP, Stone M, Levy CN, Huang ML, Roychoudhury P, Hladik F, Jerome KR, Kiem HP, Henrich TJ, Deeks SG, Lee SA. Siegel DA, et al. Among authors: roychoudhury p. AIDS. 2023 Mar 1;37(3):477-488. doi: 10.1097/QAD.0000000000003428. Epub 2022 Nov 18. AIDS. 2023. PMID: 36695358 Free PMC article.
Differences in expression of tumor suppressor, innate immune, inflammasome, and potassium/gap junction channel host genes significantly predict viral reservoir size during treated HIV infection.
Dwivedi AK, Siegel DA, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Levy CN, Roychoudhury P, Hladik F, Jerome KR, Henrich TJ, Deeks SG, Lee SA. Dwivedi AK, et al. Among authors: roychoudhury p. bioRxiv [Preprint]. 2023 Jan 12:2023.01.10.523535. doi: 10.1101/2023.01.10.523535. bioRxiv. 2023. PMID: 36712077 Free PMC article. Preprint.
A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size.
Dwivedi AK, Gornalusse GG, Siegel DA, Barbehenn A, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Reppetti J, Vo PM, Levy CN, Roychoudhury P, Jerome KR, Hladik F, Henrich TJ, Deeks SG, Lee SA. Dwivedi AK, et al. Among authors: roychoudhury p. PLoS Pathog. 2023 Nov 29;19(11):e1011114. doi: 10.1371/journal.ppat.1011114. eCollection 2023 Nov. PLoS Pathog. 2023. PMID: 38019897 Free PMC article.
Dual-strain genital herpes simplex virus type 2 (HSV-2) infection in the US, Peru, and 8 countries in sub-Saharan Africa: A nested cross-sectional viral genotyping study.
Johnston C, Magaret A, Roychoudhury P, Greninger AL, Reeves D, Schiffer J, Jerome KR, Sather C, Diem K, Lingappa JR, Celum C, Koelle DM, Wald A. Johnston C, et al. Among authors: roychoudhury p. PLoS Med. 2017 Dec 27;14(12):e1002475. doi: 10.1371/journal.pmed.1002475. eCollection 2017 Dec. PLoS Med. 2017. PMID: 29281620 Free PMC article.
CRISPR/Cas9 and Genome Editing for Viral Disease-Is Resistance Futile?
De Silva Feelixge HS, Stone D, Roychoudhury P, Aubert M, Jerome KR. De Silva Feelixge HS, et al. Among authors: roychoudhury p. ACS Infect Dis. 2018 Jun 8;4(6):871-880. doi: 10.1021/acsinfecdis.7b00273. Epub 2018 Mar 21. ACS Infect Dis. 2018. PMID: 29522311 Free PMC article. Review.
226 results