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Odiparcil, a potential glycosaminoglycans clearance therapy in mucopolysaccharidosis VI-Evidence from in vitro and in vivo models.
PLoS One. 2020 May 15;15(5):e0233032. doi: 10.1371/journal.pone.0233032. eCollection 2020.
PLoS One. 2020.
PMID: 32413051
Free PMC article.
The new-generation pan-peroxisome proliferator-activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis.
Wettstein G, Luccarini JM, Poekes L, Faye P, Kupkowski F, Adarbes V, Defrêne E, Estivalet C, Gawronski X, Jantzen I, Philippot A, Tessier J, Tuyaa-Boustugue P, Oakley F, Mann DA, Leclercq I, Francque S, Konstantinova I, Broqua P, Junien JL.
Wettstein G, et al. Among authors: jantzen i.
Hepatol Commun. 2017 Jun 19;1(6):524-537. doi: 10.1002/hep4.1057. eCollection 2017 Aug.
Hepatol Commun. 2017.
PMID: 29404476
Free PMC article.
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MPS VI associated ocular phenotypes in an MPS VI murine model and the therapeutic effects of odiparcil treatment.
Entchev E, Antonelli S, Mauro V, Cimbolini N, Jantzen I, Roussey A, Germain JM, Zhang H, Luccarrini JM, Lacombe O, Young SP, Feraille L, Tallandier M.
Entchev E, et al. Among authors: jantzen i.
Mol Genet Metab. 2022 Feb;135(2):143-153. doi: 10.1016/j.ymgme.2021.07.008. Epub 2021 Jul 25.
Mol Genet Metab. 2022.
PMID: 34417096
Free article.
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Reduction of lysosome abundance and GAG accumulation after odiparcil treatment in MPS I and MPS VI models.
Tuyaa-Boustugue P, Jantzen I, Zhang H, Young SP, Broqua P, Tallandier M, Entchev E.
Tuyaa-Boustugue P, et al. Among authors: jantzen i.
Mol Genet Metab Rep. 2023 Oct 11;37:101011. doi: 10.1016/j.ymgmr.2023.101011. eCollection 2023 Dec.
Mol Genet Metab Rep. 2023.
PMID: 38053941
Free PMC article.
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