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3,102 results

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Disulfiram Treatment Normalizes Body Weight in Obese Mice.
Bernier M, Mitchell SJ, Wahl D, Diaz A, Singh A, Seo W, Wang M, Ali A, Kaiser T, Price NL, Aon MA, Kim EY, Petr MA, Cai H, Warren A, Di Germanio C, Di Francesco A, Fishbein K, Guiterrez V, Harney D, Koay YC, Mach J, Enamorado IN, Pulpitel T, Wang Y, Zhang J, Zhang L, Spencer RG, Becker KG, Egan JM, Lakatta EG, O'Sullivan J, Larance M, LeCouteur DG, Cogger VC, Gao B, Fernandez-Hernando C, Cuervo AM, de Cabo R. Bernier M, et al. Among authors: diaz a. Cell Metab. 2020 Aug 4;32(2):203-214.e4. doi: 10.1016/j.cmet.2020.04.019. Epub 2020 May 14. Cell Metab. 2020. PMID: 32413333 Free PMC article.
Lysosomal mTORC2/PHLPP1/Akt Regulate Chaperone-Mediated Autophagy.
Arias E, Koga H, Diaz A, Mocholi E, Patel B, Cuervo AM. Arias E, et al. Among authors: diaz a. Mol Cell. 2015 Jul 16;59(2):270-84. doi: 10.1016/j.molcel.2015.05.030. Epub 2015 Jun 25. Mol Cell. 2015. PMID: 26118642 Free PMC article.
Humanin is an endogenous activator of chaperone-mediated autophagy.
Gong Z, Tasset I, Diaz A, Anguiano J, Tas E, Cui L, Kuliawat R, Liu H, Kühn B, Cuervo AM, Muzumdar R. Gong Z, et al. Among authors: diaz a. J Cell Biol. 2018 Feb 5;217(2):635-647. doi: 10.1083/jcb.201606095. Epub 2017 Nov 29. J Cell Biol. 2018. PMID: 29187525 Free PMC article.
Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans.
Walters RO, Arias E, Diaz A, Burgos ES, Guan F, Tiano S, Mao K, Green CL, Qiu Y, Shah H, Wang D, Hudgins AD, Tabrizian T, Tosti V, Shechter D, Fontana L, Kurland IJ, Barzilai N, Cuervo AM, Promislow DEL, Huffman DM. Walters RO, et al. Among authors: diaz a. Cell Rep. 2018 Oct 16;25(3):663-676.e6. doi: 10.1016/j.celrep.2018.09.065. Cell Rep. 2018. PMID: 30332646 Free PMC article.
Proteome-wide analysis of chaperone-mediated autophagy targeting motifs.
Kirchner P, Bourdenx M, Madrigal-Matute J, Tiano S, Diaz A, Bartholdy BA, Will B, Cuervo AM. Kirchner P, et al. Among authors: diaz a. PLoS Biol. 2019 May 31;17(5):e3000301. doi: 10.1371/journal.pbio.3000301. eCollection 2019 May. PLoS Biol. 2019. PMID: 31150375 Free PMC article.
Cav-1 (Caveolin-1) Deficiency Increases Autophagy in the Endothelium and Attenuates Vascular Inflammation and Atherosclerosis.
Zhang X, Ramírez CM, Aryal B, Madrigal-Matute J, Liu X, Diaz A, Torrecilla-Parra M, Suárez Y, Cuervo AM, Sessa WC, Fernández-Hernando C. Zhang X, et al. Among authors: diaz a. Arterioscler Thromb Vasc Biol. 2020 Jun;40(6):1510-1522. doi: 10.1161/ATVBAHA.120.314291. Epub 2020 Apr 30. Arterioscler Thromb Vasc Biol. 2020. PMID: 32349535 Free PMC article.
Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome.
Bernier M, Harney D, Koay YC, Diaz A, Singh A, Wahl D, Pulpitel T, Ali A, Guiterrez V, Mitchell SJ, Kim EY, Mach J, Price NL, Aon MA, LeCouteur DG, Cogger VC, Fernandez-Hernando C, O'Sullivan J, Larance M, Cuervo AM, de Cabo R. Bernier M, et al. Among authors: diaz a. NPJ Aging Mech Dis. 2020 Jul 21;6:8. doi: 10.1038/s41514-020-0046-6. eCollection 2020. NPJ Aging Mech Dis. 2020. PMID: 32714562 Free PMC article.
Reciprocal regulation of chaperone-mediated autophagy and the circadian clock.
Juste YR, Kaushik S, Bourdenx M, Aflakpui R, Bandyopadhyay S, Garcia F, Diaz A, Lindenau K, Tu V, Krause GJ, Jafari M, Singh R, Muñoz J, Macian F, Cuervo AM. Juste YR, et al. Among authors: diaz a. Nat Cell Biol. 2021 Dec;23(12):1255-1270. doi: 10.1038/s41556-021-00800-z. Epub 2021 Dec 7. Nat Cell Biol. 2021. PMID: 34876687 Free PMC article.
3,102 results