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Robust antibody and cellular responses induced by DNA-only vaccination for HIV.
De Rosa SC, Edupuganti S, Huang Y, Han X, Elizaga M, Swann E, Polakowski L, Kalams SA, Keefer MC, Maenza J, Lu Y, Wise MC, Yan J, Morrow MP, Khan AS, Boyer JD, Humeau L, White S, Pensiero M, Sardesai NY, Bagarazzi ML, Weiner DB, Ferrari G, Tomaras GD, Montefiori DC, Corey L, McElrath MJ; HIV Vaccine Trials Network (HVTN) 098 Study Team. De Rosa SC, et al. Among authors: bagarazzi ml. JCI Insight. 2020 Jul 9;5(13):e137079. doi: 10.1172/jci.insight.137079. JCI Insight. 2020. PMID: 32437332 Free PMC article.
Synthetic consensus HIV-1 DNA induces potent cellular immune responses and synthesis of granzyme B, perforin in HIV infected individuals.
Morrow MP, Tebas P, Yan J, Ramirez L, Slager A, Kraynyak K, Diehl M, Shah D, Khan A, Lee J, Boyer J, Kim JJ, Sardesai NY, Weiner DB, Bagarazzi ML. Morrow MP, et al. Among authors: bagarazzi ml. Mol Ther. 2015 Mar;23(3):591-601. doi: 10.1038/mt.2014.245. Epub 2014 Dec 22. Mol Ther. 2015. PMID: 25531694 Free PMC article.
Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses.
Bagarazzi ML, Yan J, Morrow MP, Shen X, Parker RL, Lee JC, Giffear M, Pankhong P, Khan AS, Broderick KE, Knott C, Lin F, Boyer JD, Draghia-Akli R, White CJ, Kim JJ, Weiner DB, Sardesai NY. Bagarazzi ML, et al. Sci Transl Med. 2012 Oct 10;4(155):155ra138. doi: 10.1126/scitranslmed.3004414. Sci Transl Med. 2012. PMID: 23052295 Free PMC article. Clinical Trial.
Augmentation of cellular and humoral immune responses to HPV16 and HPV18 E6 and E7 antigens by VGX-3100.
Morrow MP, Kraynyak KA, Sylvester AJ, Shen X, Amante D, Sakata L, Parker L, Yan J, Boyer J, Roh C, Humeau L, Khan AS, Broderick K, Marcozzi-Pierce K, Giffear M, Lee J, Trimble CL, Kim JJ, Sardesai NY, Weiner DB, Bagarazzi ML. Morrow MP, et al. Among authors: bagarazzi ml. Mol Ther Oncolytics. 2016 Nov 30;3:16025. doi: 10.1038/mto.2016.25. eCollection 2016. Mol Ther Oncolytics. 2016. PMID: 28054033 Free PMC article.
Clinical and Immunologic Biomarkers for Histologic Regression of High-Grade Cervical Dysplasia and Clearance of HPV16 and HPV18 after Immunotherapy.
Morrow MP, Kraynyak KA, Sylvester AJ, Dallas M, Knoblock D, Boyer JD, Yan J, Vang R, Khan AS, Humeau L, Sardesai NY, Kim JJ, Plotkin S, Weiner DB, Trimble CL, Bagarazzi ML. Morrow MP, et al. Among authors: bagarazzi ml. Clin Cancer Res. 2018 Jan 15;24(2):276-294. doi: 10.1158/1078-0432.CCR-17-2335. Epub 2017 Oct 30. Clin Cancer Res. 2018. PMID: 29084917 Free PMC article.
Intramuscular and Intradermal Electroporation of HIV-1 PENNVAX-GP® DNA Vaccine and IL-12 Is Safe, Tolerable, Acceptable in Healthy Adults.
Edupuganti S, C De Rosa S, Elizaga M, Lu Y, Han X, Huang Y, Swann E, Polakowski L, A Kalams S, Keefer M, Maenza J, C Wise M, Yan J, Morrow MP, Khan AS, Boyer JD, Humeau L, White S, Sardesai NY, Bagarazzi ML, Gilbert PB, Kublin JG, Corey L, Weiner DB, On Behalf Of The Hvtn Study Team, The Niaid-Funded Hiv Vaccine Trials Network. Edupuganti S, et al. Among authors: bagarazzi ml. Vaccines (Basel). 2020 Dec 7;8(4):741. doi: 10.3390/vaccines8040741. Vaccines (Basel). 2020. PMID: 33297341 Free PMC article.
Next generation DNA vaccines for HIV-1.
Boyer JD, Chattergoon M, Muthumani K, Kudchodkar S, Kim J, Bagarazzi M, Pavlakis G, Sekaly R, Weiner DB. Boyer JD, et al. J Liposome Res. 2002 Feb-May;12(1-2):137-42. doi: 10.1081/lpr-120004786. J Liposome Res. 2002. PMID: 12604047 Review.
Intradermal SynCon® Ebola GP DNA Vaccine Is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers.
Tebas P, Kraynyak KA, Patel A, Maslow JN, Morrow MP, Sylvester AJ, Knoblock D, Gillespie E, Amante D, Racine T, McMullan T, Jeong M, Roberts CC, Park YK, Boyer J, Broderick KE, Kobinger GP, Bagarazzi M, Weiner DB, Sardesai NY, White SM. Tebas P, et al. J Infect Dis. 2019 Jul 2;220(3):400-410. doi: 10.1093/infdis/jiz132. J Infect Dis. 2019. PMID: 30891607
Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine.
Tebas P, Roberts CC, Muthumani K, Reuschel EL, Kudchodkar SB, Zaidi FI, White S, Khan AS, Racine T, Choi H, Boyer J, Park YK, Trottier S, Remigio C, Krieger D, Spruill SE, Bagarazzi M, Kobinger GP, Weiner DB, Maslow JN. Tebas P, et al. N Engl J Med. 2021 Sep 16;385(12):e35. doi: 10.1056/NEJMoa1708120. N Engl J Med. 2021. PMID: 34525286 Free PMC article. Clinical Trial.
43 results