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Prediction of Drug Exposure in Critically Ill Encephalopathic Neonates Treated With Therapeutic Hypothermia Based on a Pooled Population Pharmacokinetic Analysis of Seven Drugs and Five Metabolites.
Favié LMA, de Haan TR, Bijleveld YA, Rademaker CMA, Egberts TCG, Nuytemans DHGM, Mathôt RAA, Groenendaal F, Huitema ADR. Favié LMA, et al. Clin Pharmacol Ther. 2020 Nov;108(5):1098-1106. doi: 10.1002/cpt.1917. Epub 2020 Jun 27. Clin Pharmacol Ther. 2020. PMID: 32463940 Free PMC article.
Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia.
Favié LMA, Groenendaal F, van den Broek MPH, Rademaker CMA, de Haan TR, van Straaten HLM, Dijk PH, van Heijst A, Dudink J, Dijkman KP, Rijken M, Zonnenberg IA, Cools F, Zecic A, van der Lee JH, Nuytemans DHGM, van Bel F, Egberts TCG, Huitema ADR; PharmaCool study group. Favié LMA, et al. PLoS One. 2019 Feb 14;14(2):e0211910. doi: 10.1371/journal.pone.0211910. eCollection 2019. PLoS One. 2019. PMID: 30763356 Free PMC article. Clinical Trial.
Lidocaine as treatment for neonatal seizures: Evaluation of previously developed population pharmacokinetic models and dosing regimen.
Favié LMA, Huitema ADR, van den Broek MPH, Rademaker CMA, de Haan TR, van Straaten HLM, Simons SHP, Rijken M, Nuytemans DHGM, Egberts TCG, Groenendaal F; PharmaCool study group*. Favié LMA, et al. Br J Clin Pharmacol. 2020 Jan;86(1):75-84. doi: 10.1111/bcp.14136. Epub 2020 Jan 3. Br J Clin Pharmacol. 2020. PMID: 31663153 Free PMC article.
Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.
Favié LMA, Groenendaal F, van den Broek MPH, Rademaker CMA, de Haan TR, van Straaten HLM, Dijk PH, van Heijst A, Simons SHP, Dijkman KP, Rijken M, Zonnenberg IA, Cools F, Zecic A, van der Lee JH, Nuytemans DHGM, van Bel F, Egberts TCG, Huitema ADR; on behalf of the PharmaCool study group. Favié LMA, et al. Neonatology. 2019;116(2):154-162. doi: 10.1159/000499330. Epub 2019 Jun 28. Neonatology. 2019. PMID: 31256150 Free PMC article.
Translation from animal to clinical studies, choosing the optimal moment.
Favié LMA, Peeters-Scholte CMPCD, Bakker A, Tjabbes H, Egberts TCG, van Bel F, Rademaker CMA, Vis P, Groenendaal F. Favié LMA, et al. Pediatr Res. 2020 Dec;88(6):836-837. doi: 10.1038/s41390-020-0820-y. Epub 2020 Feb 19. Pediatr Res. 2020. PMID: 32074625 No abstract available.
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