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Page 1
The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells.
Corzo CA, Varfolomeev E, Setiadi AF, Francis R, Klabunde S, Senger K, Sujatha-Bhaskar S, Drobnick J, Do S, Suto E, Huang Z, Eastham-Anderson J, Katewa A, Pang J, Domeyer M, Dela Cruz C, Paler-Martinez A, Lau VWC, Hadadianpour A, Ramirez-Carrozi V, Sun Y, Bao K, Xu D, Hunley E, Brightbill HD, Warming S, Roose-Girma M, Wong A, Tam L, Emson CL, Crawford JJ, Young WB, Pappu R, McKenzie BS, Asghari V, Vucic D, Hackney JA, Austin CD, Lee WP, Lekkerkerker A, Ghilardi N, Bryan MC, Kiefer JR, Townsend MJ, Zarrin AA. Corzo CA, et al. Among authors: eastham anderson j. Sci Signal. 2020 Jun 2;13(634):eaaz1053. doi: 10.1126/scisignal.aaz1053. Sci Signal. 2020. PMID: 32487715
Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response.
Sun Y, Peng I, Webster JD, Suto E, Lesch J, Wu X, Senger K, Francis G, Barrett K, Collier JL, Burch JD, Zhou M, Chen Y, Chan C, Eastham-Anderson J, Ngu H, Li O, Staton T, Havnar C, Jaochico A, Jackman J, Jeet S, Riol-Blanco L, Wu LC, Choy DF, Arron JR, McKenzie BS, Ghilardi N, Ismaili MH, Pei Z, DeVoss J, Austin CD, Lee WP, Zarrin AA. Sun Y, et al. Sci Signal. 2015 Dec 1;8(405):ra122. doi: 10.1126/scisignal.aab0949. Sci Signal. 2015. PMID: 26628680
IL-33 amplifies an innate immune response in the degenerating retina.
Xi H, Katschke KJ Jr, Li Y, Truong T, Lee WP, Diehl L, Rangell L, Tao J, Arceo R, Eastham-Anderson J, Hackney JA, Iglesias A, Cote-Sierra J, Elstrott J, Weimer RM, van Lookeren Campagne M. Xi H, et al. J Exp Med. 2016 Feb 8;213(2):189-207. doi: 10.1084/jem.20150894. Epub 2016 Jan 11. J Exp Med. 2016. PMID: 26755704 Free PMC article.
Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1.
Spooner CJ, Lesch J, Yan D, Khan AA, Abbas A, Ramirez-Carrozzi V, Zhou M, Soriano R, Eastham-Anderson J, Diehl L, Lee WP, Modrusan Z, Pappu R, Xu M, DeVoss J, Singh H. Spooner CJ, et al. Nat Immunol. 2013 Dec;14(12):1229-36. doi: 10.1038/ni.2743. Epub 2013 Oct 20. Nat Immunol. 2013. PMID: 24141388
Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.
Lafkas D, Shelton A, Chiu C, de Leon Boenig G, Chen Y, Stawicki SS, Siltanen C, Reichelt M, Zhou M, Wu X, Eastham-Anderson J, Moore H, Roose-Girma M, Chinn Y, Hang JQ, Warming S, Egen J, Lee WP, Austin C, Wu Y, Payandeh J, Lowe JB, Siebel CW. Lafkas D, et al. Nature. 2015 Dec 3;528(7580):127-31. doi: 10.1038/nature15715. Epub 2015 Nov 18. Nature. 2015. PMID: 26580007
CRIg mediates early Kupffer cell responses to adenovirus.
He JQ, Katschke KJ Jr, Gribling P, Suto E, Lee WP, Diehl L, Eastham-Anderson J, Ponakala A, Komuves L, Egen JG, van Lookeren Campagne M. He JQ, et al. J Leukoc Biol. 2013 Feb;93(2):301-6. doi: 10.1189/jlb.0612311. Epub 2012 Dec 5. J Leukoc Biol. 2013. PMID: 23225913
Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1.
He M, Chaurushiya MS, Webster JD, Kummerfeld S, Reja R, Chaudhuri S, Chen YJ, Modrusan Z, Haley B, Dugger DL, Eastham-Anderson J, Lau S, Dey A, Caothien R, Roose-Girma M, Newton K, Dixit VM. He M, et al. Among authors: eastham anderson j. Science. 2019 Apr 19;364(6437):283-285. doi: 10.1126/science.aav4902. Epub 2019 Apr 18. Science. 2019. PMID: 31000662
58 results