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LY6E impairs coronavirus fusion and confers immune control of viral disease.
Pfaender S, Mar KB, Michailidis E, Kratzel A, Hirt D, V'kovski P, Fan W, Ebert N, Stalder H, Kleine-Weber H, Hoffmann M, Hoffmann HH, Saeed M, Dijkman R, Steinmann E, Wight-Carter M, Hanners NW, Pöhlmann S, Gallagher T, Todt D, Zimmer G, Rice CM, Schoggins JW, Thiel V. Pfaender S, et al. Among authors: hoffmann m, hoffmann hh. bioRxiv [Preprint]. 2020 Mar 7:2020.03.05.979260. doi: 10.1101/2020.03.05.979260. bioRxiv. 2020. PMID: 32511345 Free PMC article. Updated. Preprint.
Organotypic human lung bud microarrays identify BMP-dependent SARS-CoV-2 infection in lung cells.
Rosado-Olivieri EA, Razooky B, Le Pen J, De Santis R, Barrows D, Sabry Z, Hoffmann HH, Park J, Carroll TS, Poirier JT, Rice CM, Brivanlou AH. Rosado-Olivieri EA, et al. Among authors: hoffmann hh. Stem Cell Reports. 2023 May 9;18(5):1107-1122. doi: 10.1016/j.stemcr.2023.03.015. Epub 2023 Apr 20. Stem Cell Reports. 2023. PMID: 37084725 Free PMC article.
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses.
Cervantes Rincón T, Kapoor T, Keeffe JR, Simonelli L, Hoffmann HH, Agudelo M, Jurado A, Peace A, Lee YE, Gazumyan A, Guidetti F, Cantergiani J, Cena B, Bianchini F, Tamagnini E, Moro SG, Svoboda P, Costa F, Reis MG, Ko AI, Fallon BA, Avila-Rios S, Reyes-Téran G, Rice CM, Nussenzweig MC, Bjorkman PJ, Ruzek D, Varani L, MacDonald MR, Robbiani DF. Cervantes Rincón T, et al. Among authors: hoffmann hh. Cell Rep. 2024 May 29;43(6):114298. doi: 10.1016/j.celrep.2024.114298. Online ahead of print. Cell Rep. 2024. PMID: 38819991 Free article.
Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies.
Zang T, Osei Kuffour E, Baharani VA, Canis M, Schmidt F, Da Silva J, Lercher A, Chaudhary P, Hoffmann HH, Gazumyan A, Miranda IC, MacDonald MR, Rice CM, Nussenzweig MC, Hatziioannou T, Bieniasz PD. Zang T, et al. Among authors: hoffmann hh. Proc Natl Acad Sci U S A. 2023 Dec 19;120(51):e2317367120. doi: 10.1073/pnas.2317367120. Epub 2023 Dec 14. Proc Natl Acad Sci U S A. 2023. PMID: 38096415 Free PMC article.
Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection.
Lercher A, Cheong JG, Jiang C, Hoffmann HH, Ashbrook AW, Yin YS, Quirk C, DeGrace EJ, Chiriboga L, Rosenberg BR, Josefowicz SZ, Rice CM. Lercher A, et al. Among authors: hoffmann hh. bioRxiv [Preprint]. 2023 Nov 27:2023.11.24.568354. doi: 10.1101/2023.11.24.568354. bioRxiv. 2023. PMID: 38076887 Free PMC article. Preprint.
Pan-sarbecovirus prophylaxis with human anti-ACE2 monoclonal antibodies.
Zhang F, Jenkins J, de Carvalho RVH, Nakandakari-Higa S, Chen T, Abernathy ME, Baharani VA, Nyakatura EK, Andrew D, Lebedeva IV, Lorenz IC, Hoffmann HH, Rice CM, Victora GD, Barnes CO, Hatziioannou T, Bieniasz PD. Zhang F, et al. Among authors: hoffmann hh. Nat Microbiol. 2023 Jun;8(6):1051-1063. doi: 10.1038/s41564-023-01389-9. Epub 2023 May 15. Nat Microbiol. 2023. PMID: 37188812 Free PMC article.
75 results