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6 results
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Phase I Trial of First-in-Class ATR Inhibitor M6620 (VX-970) as Monotherapy or in Combination With Carboplatin in Patients With Advanced Solid Tumors.
J Clin Oncol. 2020 Sep 20;38(27):3195-3204. doi: 10.1200/JCO.19.02404. Epub 2020 Jun 22.
J Clin Oncol. 2020.
PMID: 32568634
Free PMC article.
Clinical Trial.
Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases.
Farmer LJ, Ledeboer MW, Hoock T, Arnost MJ, Bethiel RS, Bennani YL, Black JJ, Brummel CL, Chakilam A, Dorsch WA, Fan B, Cochran JE, Halas S, Harrington EM, Hogan JK, Howe D, Huang H, Jacobs DH, Laitinen LM, Liao S, Mahajan S, Marone V, Martinez-Botella G, McCarthy P, Messersmith D, Namchuk M, Oh L, Penney MS, Pierce AC, Raybuck SA, Rugg A, Salituro FG, Saxena K, Shannon D, Shlyakter D, Swenson L, Tian SK, Town C, Wang J, Wang T, Wannamaker MW, Winquist RJ, Zuccola HJ.
Farmer LJ, et al. Among authors: penney ms.
J Med Chem. 2015 Sep 24;58(18):7195-216. doi: 10.1021/acs.jmedchem.5b00301. Epub 2015 Sep 10.
J Med Chem. 2015.
PMID: 26230873
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Successful treatment with telaprevir-based regimens for chronic hepatitis C results in significant improvements to serum markers of liver fibrosis.
Haseltine EL, Penney MS, George S, Kieffer TL.
Haseltine EL, et al. Among authors: penney ms.
J Viral Hepat. 2015 Sep;22(9):701-7. doi: 10.1111/jvh.12382. Epub 2015 Jan 13.
J Viral Hepat. 2015.
PMID: 25582683
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Telaprevir-based treatment effects on hepatitis C virus in liver and blood.
Talal AH, Dimova RB, Zhang EZ, Jiang M, Penney MS, Sullivan JC, Botfield MC, Chakilam A, Sawant R, Cervini CM, Zeremski M, Jacobson IM, Kwong AD.
Talal AH, et al. Among authors: penney ms.
Hepatology. 2014 Dec;60(6):1826-37. doi: 10.1002/hep.27202. Epub 2014 Jul 31.
Hepatology. 2014.
PMID: 24811404
Free PMC article.
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Intrahepatic and Peripheral CXCL10 Expression in Hepatitis C Virus-Infected Patients Treated With Telaprevir, Pegylated Interferon, and Ribavirin.
Zeremski M, Dimova RB, Benjamin S, Penney MS, Botfield MC, Talal AH.
Zeremski M, et al. Among authors: penney ms.
J Infect Dis. 2015 Jun 1;211(11):1795-9. doi: 10.1093/infdis/jiu807. Epub 2014 Dec 15.
J Infect Dis. 2015.
PMID: 25512630
Free PMC article.
Clinical Trial.
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Modelling natural burst firing in nigral dopamine neurons.
Penney MS, Britton NF.
Penney MS, et al.
J Theor Biol. 2002 Nov 21;219(2):207-23. doi: 10.1006/jtbi.2002.3116.
J Theor Biol. 2002.
PMID: 12413876
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