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Phase I Trial of First-in-Class ATR Inhibitor M6620 (VX-970) as Monotherapy or in Combination With Carboplatin in Patients With Advanced Solid Tumors.
Yap TA, O'Carrigan B, Penney MS, Lim JS, Brown JS, de Miguel Luken MJ, Tunariu N, Perez-Lopez R, Rodrigues DN, Riisnaes R, Figueiredo I, Carreira S, Hare B, McDermott K, Khalique S, Williamson CT, Natrajan R, Pettitt SJ, Lord CJ, Banerji U, Pollard J, Lopez J, de Bono JS. Yap TA, et al. Among authors: de miguel luken mj. J Clin Oncol. 2020 Sep 20;38(27):3195-3204. doi: 10.1200/JCO.19.02404. Epub 2020 Jun 22. J Clin Oncol. 2020. PMID: 32568634 Free PMC article. Clinical Trial.
Clinical outcomes and prognostic factors of patients with advanced mesothelioma treated in a phase I clinical trials unit.
Papadatos-Pastos D, Roda D, De Miguel Luken MJ, Petruckevitch A, Jalil A, Capelan M, Michalarea V, Lima J, Diamantis N, Bhosle J, Molife LR, Banerji U, de Bono JS, Popat S, O'Brien MER, Yap TA. Papadatos-Pastos D, et al. Among authors: de miguel luken mj. Eur J Cancer. 2017 Apr;75:56-62. doi: 10.1016/j.ejca.2016.12.026. Epub 2017 Feb 17. Eur J Cancer. 2017. PMID: 28214659
Combining targeted therapeutics in the era of precision medicine.
Papadatos-Pastos D, De Miguel Luken MJ, Yap TA. Papadatos-Pastos D, et al. Among authors: de miguel luken mj. Br J Cancer. 2015 Jan 6;112(1):1-3. doi: 10.1038/bjc.2014.558. Br J Cancer. 2015. PMID: 25562565 Free PMC article. No abstract available.
First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors.
Kim TW, Burris HA, de Miguel Luken MJ, Pishvaian MJ, Bang YJ, Gordon M, Awada A, Camidge DR, Hodi FS, McArthur GA, Miller WH, Cervantes A, Chow LQ, Lesokhin AM, Rutten A, Sznol M, Rishipathak D, Chen SC, Stefanich E, Pourmohamad T, Anderson M, Kim J, Huseni M, Rhee I, Siu LL. Kim TW, et al. Among authors: de miguel luken mj. Clin Cancer Res. 2022 Aug 15;28(16):3452-3463. doi: 10.1158/1078-0432.CCR-21-4020. Clin Cancer Res. 2022. PMID: 35699599 Free PMC article. Clinical Trial.
Effect of ceritinib on the pharmacokinetics of coadministered CYP3A and 2C9 substrates: a phase I, multicenter, drug-drug interaction study in patients with ALK + advanced tumors.
Hurtado FK, de Braud F, De Castro Carpeño J, de Miguel Luken MJ, Wang D, Scott J, Lau YY, McCulloch T, Mau-Sorensen M. Hurtado FK, et al. Among authors: de miguel luken mj. Cancer Chemother Pharmacol. 2021 Apr;87(4):475-486. doi: 10.1007/s00280-020-04180-3. Epub 2021 Jan 4. Cancer Chemother Pharmacol. 2021. PMID: 33394101 Free PMC article. Clinical Trial.
Tolerability and antitumor activity of cemiplimab, a human monoclonal anti-PD-1, as monotherapy in patients with pretreated non-small cell lung cancer (NSCLC): Data from the Phase 1 NSCLC expansion cohort.
Moreno V, Garrido P, Papadopoulos KP, De Miguel Luken MJ, Gil-Martin M, Aljumaily R, Rosen LS, Rietschel P, Mohan KK, Yoo SY, Stankevich E, Lowy I, Fury MG. Moreno V, et al. Among authors: de miguel luken mj. Lung Cancer. 2021 May;155:151-155. doi: 10.1016/j.lungcan.2021.02.034. Epub 2021 Mar 4. Lung Cancer. 2021. PMID: 33831732 Clinical Trial.
A genetic view of laryngeal cancer heterogeneity.
de Miguel-Luken MJ, Chaves-Conde M, Carnero A. de Miguel-Luken MJ, et al. Cell Cycle. 2016 May 2;15(9):1202-12. doi: 10.1080/15384101.2016.1156275. Epub 2016 Mar 3. Cell Cycle. 2016. PMID: 26940775 Free PMC article. Review.
MAP17 (PDZKIP1) as a novel prognostic biomarker for laryngeal cancer.
de Miguel-Luken MJ, Chaves-Conde M, de Miguel-Luken V, Muñoz-Galván S, López-Guerra JL, Mateos JC, Pachón J, Chinchón D, Suarez V, Carnero A. de Miguel-Luken MJ, et al. Oncotarget. 2015 May 20;6(14):12625-36. doi: 10.18632/oncotarget.3470. Oncotarget. 2015. PMID: 25788275 Free PMC article.
12 results