Gravells P - Search Results

1

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma.

King D, Li XD, Almeida GS, Kwok C, Gravells P, Harrison D, Burke S, Hallsworth A, Jamin Y, George S, Robinson SP, Lord CJ, Poon E, Yeomanson D, Chesler L, Bryant HE. King D, et al. Among authors: gravells p. Oncotarget. 2020 Jun 9;11(23):2141-2159. doi: 10.18632/oncotarget.27329. eCollection 2020 Jun 9. Oncotarget. 2020. PMID: 32577161 Free PMC article.

2

DNA Fiber Assay for the Analysis of DNA Replication Progression in Human Pluripotent Stem Cells.

Halliwell JA, Gravells P, Bryant HE. Halliwell JA, et al. Among authors: gravells p. Curr Protoc Stem Cell Biol. 2020 Sep;54(1):e115. doi: 10.1002/cpsc.115. Curr Protoc Stem Cell Biol. 2020. PMID: 32584505 Free article.

3

Poly(ADP-Ribose) Glycohydrolase (PARG) vs. Poly(ADP-Ribose) Polymerase (PARP) - Function in Genome Maintenance and Relevance of Inhibitors for Anti-cancer Therapy.

Harrision D, Gravells P, Thompson R, Bryant HE. Harrision D, et al. Among authors: gravells p. Front Mol Biosci. 2020 Aug 28;7:191. doi: 10.3389/fmolb.2020.00191. eCollection 2020. Front Mol Biosci. 2020. PMID: 33005627 Free PMC article. Review.

4

Increased Replication Stress Determines ATR Inhibitor Sensitivity in Neuroblastoma Cells.

King D, Southgate HED, Roetschke S, Gravells P, Fields L, Watson JB, Chen L, Chapman D, Harrison D, Yeomanson D, Curtin NJ, Tweddle DA, Bryant HE. King D, et al. Among authors: gravells p. Cancers (Basel). 2021 Dec 10;13(24):6215. doi: 10.3390/cancers13246215. Cancers (Basel). 2021. PMID: 34944835 Free PMC article.

5

Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase.

Gravells P, Grant E, Smith KM, James DI, Bryant HE. Gravells P, et al. DNA Repair (Amst). 2017 Apr;52:81-91. doi: 10.1016/j.dnarep.2017.02.010. Epub 2017 Feb 17. DNA Repair (Amst). 2017. PMID: 28254358 Free PMC article.

6

Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib.

Gravells P, Neale J, Grant E, Nathubhai A, Smith KM, James DI, Bryant HE. Gravells P, et al. DNA Repair (Amst). 2018 Jan;61:25-36. doi: 10.1016/j.dnarep.2017.11.004. Epub 2017 Nov 22. DNA Repair (Amst). 2018. PMID: 29179156 Free PMC article.

7

Resistance of uveal melanoma to the interstrand cross-linking agent mitomycin C is associated with reduced expression of CYP450R.

Gravells P, Hoh L, Canovas D, Rennie IG, Sisley K, Bryant HE. Gravells P, et al. Br J Cancer. 2011 Mar 29;104(7):1098-105. doi: 10.1038/bjc.2011.56. Epub 2011 Mar 8. Br J Cancer. 2011. PMID: 21386838 Free PMC article.

8

Reduced FANCD2 influences spontaneous SCE and RAD51 foci formation in uveal melanoma and Fanconi anaemia.

Gravells P, Hoh L, Solovieva S, Patil A, Dudziec E, Rennie IG, Sisley K, Bryant HE. Gravells P, et al. Oncogene. 2013 Nov 14;32(46):5338-46. doi: 10.1038/onc.2012.627. Epub 2013 Jan 14. Oncogene. 2013. PMID: 23318456 Free PMC article.

9

Atypically low spontaneous sister chromatid exchange formation in uveal melanoma.

Hoh L, Gravells P, Canovas D, Ul-Hassan A, Rennie IG, Bryant H, Sisley K. Hoh L, et al. Among authors: gravells p. Genes Chromosomes Cancer. 2011 Jan;50(1):34-42. doi: 10.1002/gcc.20829. Genes Chromosomes Cancer. 2011. PMID: 20960562

10

Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.

Gravells P, Ahrabi S, Vangala RK, Tomita K, Brash JT, Brustle LA, Chung C, Hong JM, Kaloudi A, Humphrey TC, Porter AC. Gravells P, et al. Hum Mol Genet. 2015 Dec 15;24(24):7097-110. doi: 10.1093/hmg/ddv409. Epub 2015 Sep 30. Hum Mol Genet. 2015. PMID: 26423459 Free PMC article.

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