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Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike.
Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Liu L, et al. Among authors: chen z. bioRxiv [Preprint]. 2020 Jul 16:2020.06.17.153486. doi: 10.1101/2020.06.17.153486. bioRxiv. 2020. PMID: 32587975 Free PMC article. Updated. Preprint.
Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics.
Kao RY, Tsui WH, Lee TS, Tanner JA, Watt RM, Huang JD, Hu L, Chen G, Chen Z, Zhang L, He T, Chan KH, Tse H, To AP, Ng LW, Wong BC, Tsoi HW, Yang D, Ho DD, Yuen KY. Kao RY, et al. Among authors: chen z, chen g. Chem Biol. 2004 Sep;11(9):1293-9. doi: 10.1016/j.chembiol.2004.07.013. Chem Biol. 2004. PMID: 15380189 Free PMC article.
Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region.
Chen Z, Zhang L, Qin C, Ba L, Yi CE, Zhang F, Wei Q, He T, Yu W, Yu J, Gao H, Tu X, Gettie A, Farzan M, Yuen KY, Ho DD. Chen Z, et al. J Virol. 2005 Mar;79(5):2678-88. doi: 10.1128/JVI.79.5.2678-2688.2005. J Virol. 2005. PMID: 15708987 Free PMC article.
A replicating modified vaccinia tiantan strain expressing an avian-derived influenza H5N1 hemagglutinin induce broadly neutralizing antibodies and cross-clade protective immunity in mice.
Xiao H, Liu L, Zhu Q, Tan Z, Yu W, Tang X, Zhan D, Du Y, Wang H, Liu D, Li Z, Yuen KY, Ho DD, Gao GF, Chen Z. Xiao H, et al. Among authors: chen z. PLoS One. 2013 Dec 17;8(12):e83274. doi: 10.1371/journal.pone.0083274. eCollection 2013. PLoS One. 2013. PMID: 24358269 Free PMC article.
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