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Regression of Atherosclerosis in ApoE-/- Mice Via Modulation of Monocyte Recruitment and Phenotype, Induced by Weekly Dosing of a Novel "Cytotopic" Anti-Thrombin Without Prolonged Anticoagulation.
Chen D, Li K, Festenstein S, Karegli J, Wilkinson H, Leonard H, Wei LL, Ma N, Xia M, Tam H, Wang JA, Xu Q, McVey JH, Smith RAG, Dorling A. Chen D, et al. Among authors: smith rag. J Am Heart Assoc. 2020 Jul 7;9(13):e014811. doi: 10.1161/JAHA.119.014811. Epub 2020 Jul 2. J Am Heart Assoc. 2020. PMID: 32611229 Free PMC article.
Inhibition of thrombin on endothelium enhances recruitment of regulatory T cells during IRI and when combined with adoptive Treg transfer, significantly protects against acute tissue injury and prolongs allograft survival.
Peng Q, Nowocin A, Ratnasothy K, Smith RA, Smyth LA, Lechler RI, Dorling A, Lombardi G. Peng Q, et al. Front Immunol. 2023 Jan 30;13:980462. doi: 10.3389/fimmu.2022.980462. eCollection 2022. Front Immunol. 2023. PMID: 36793549 Free PMC article.
Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.
Blaskovich MAT, Hansford KA, Gong Y, Butler MS, Muldoon C, Huang JX, Ramu S, Silva AB, Cheng M, Kavanagh AM, Ziora Z, Premraj R, Lindahl F, Bradford TA, Lee JC, Karoli T, Pelingon R, Edwards DJ, Amado M, Elliott AG, Phetsang W, Daud NH, Deecke JE, Sidjabat HE, Ramaologa S, Zuegg J, Betley JR, Beevers APG, Smith RAG, Roberts JA, Paterson DL, Cooper MA. Blaskovich MAT, et al. Among authors: smith rag. Nat Commun. 2018 Jan 2;9(1):22. doi: 10.1038/s41467-017-02123-w. Nat Commun. 2018. PMID: 29295973 Free PMC article.
31 results