Xue M - Search Results

1

Development of a Convergent Enantioselective Synthetic Route to (-)-Myrocin G.

Tomanik M, Economou C, Frischling MC, Xue M, Marks VA, Mercado BQ, Herzon SB. Tomanik M, et al. Among authors: xue m. J Org Chem. 2020 Jul 17;85(14):8952-8989. doi: 10.1021/acs.joc.0c00891. Epub 2020 Jul 2. J Org Chem. 2020. PMID: 32615040 Free PMC article.

2

Mechanism of Nucleophilic Activation of (-)-Lomaiviticin A.

Xue M, Herzon SB. Xue M, et al. J Am Chem Soc. 2016 Dec 7;138(48):15559-15562. doi: 10.1021/jacs.6b09657. Epub 2016 Nov 28. J Am Chem Soc. 2016. PMID: 27934014 Free PMC article.

3

Characterization of Natural Colibactin-Nucleobase Adducts by Tandem Mass Spectrometry and Isotopic Labeling. Support for DNA Alkylation by Cyclopropane Ring Opening.

Xue M, Shine E, Wang W, Crawford JM, Herzon SB. Xue M, et al. Biochemistry. 2018 Nov 13;57(45):6391-6394. doi: 10.1021/acs.biochem.8b01023. Epub 2018 Oct 31. Biochemistry. 2018. PMID: 30365310 Free PMC article.

4

Model Colibactins Exhibit Human Cell Genotoxicity in the Absence of Host Bacteria.

Shine EE, Xue M, Patel JR, Healy AR, Surovtseva YV, Herzon SB, Crawford JM. Shine EE, et al. Among authors: xue m. ACS Chem Biol. 2018 Dec 21;13(12):3286-3293. doi: 10.1021/acschembio.8b00714. Epub 2018 Nov 20. ACS Chem Biol. 2018. PMID: 30403848 Free PMC article.

5

Structure elucidation of colibactin and its DNA cross-links.

Xue M, Kim CS, Healy AR, Wernke KM, Wang Z, Frischling MC, Shine EE, Wang W, Herzon SB, Crawford JM. Xue M, et al. Science. 2019 Sep 6;365(6457):eaax2685. doi: 10.1126/science.aax2685. Epub 2019 Aug 8. Science. 2019. PMID: 31395743 Free PMC article.

6

Depurination of Colibactin-Derived Interstrand Cross-Links.

Xue M, Wernke KM, Herzon SB. Xue M, et al. Biochemistry. 2020 Feb 25;59(7):892-900. doi: 10.1021/acs.biochem.9b01070. Epub 2020 Feb 13. Biochemistry. 2020. PMID: 31977191 Free PMC article.

7

Structure and bioactivity of colibactin.

Wernke KM, Xue M, Tirla A, Kim CS, Crawford JM, Herzon SB. Wernke KM, et al. Among authors: xue m. Bioorg Med Chem Lett. 2020 Aug 1;30(15):127280. doi: 10.1016/j.bmcl.2020.127280. Epub 2020 May 23. Bioorg Med Chem Lett. 2020. PMID: 32527463 Free PMC article. Review.

8

Structure Revision of the Lomaiviticins.

Kim LJ, Xue M, Li X, Xu Z, Paulson E, Mercado B, Nelson HM, Herzon SB. Kim LJ, et al. Among authors: xue m. J Am Chem Soc. 2021 May 5;143(17):6578-6585. doi: 10.1021/jacs.1c01729. Epub 2021 Apr 26. J Am Chem Soc. 2021. PMID: 33900077 Free PMC article.

9

Probing Microbiome Genotoxicity: A Stable Colibactin Provides Insight into Structure-Activity Relationships and Facilitates Mechanism of Action Studies.

Wernke KM, Tirla A, Xue M, Surovtseva YV, Menges FS, Herzon SB. Wernke KM, et al. Among authors: xue m. J Am Chem Soc. 2021 Sep 29;143(38):15824-15833. doi: 10.1021/jacs.1c07559. Epub 2021 Sep 15. J Am Chem Soc. 2021. PMID: 34524796

10

Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites.

Cao Y, Oh J, Xue M, Huh WJ, Wang J, Gonzalez-Hernandez JA, Rice TA, Martin AL, Song D, Crawford JM, Herzon SB, Palm NW. Cao Y, et al. Among authors: xue m. Science. 2022 Oct 28;378(6618):eabm3233. doi: 10.1126/science.abm3233. Epub 2022 Oct 28. Science. 2022. PMID: 36302024 Free PMC article.

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