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Page 1
HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease.
Cook SA, Comrie WA, Poli MC, Similuk M, Oler AJ, Faruqi AJ, Kuhns DB, Yang S, Vargas-Hernández A, Carisey AF, Fournier B, Anderson DE, Price S, Smelkinson M, Abou Chahla W, Forbes LR, Mace EM, Cao TN, Coban-Akdemir ZH, Jhangiani SN, Muzny DM, Gibbs RA, Lupski JR, Orange JS, Cuvelier GDE, Al Hassani M, Al Kaabi N, Al Yafei Z, Jyonouchi S, Raje N, Caldwell JW, Huang Y, Burkhardt JK, Latour S, Chen B, ElGhazali G, Rao VK, Chinn IK, Lenardo MJ. Cook SA, et al. Among authors: smelkinson m. Science. 2020 Jul 10;369(6500):202-207. doi: 10.1126/science.aay5663. Science. 2020. PMID: 32647003 Free PMC article.
Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury.
Harrison OJ, Linehan JL, Shih HY, Bouladoux N, Han SJ, Smelkinson M, Sen SK, Byrd AL, Enamorado M, Yao C, Tamoutounour S, Van Laethem F, Hurabielle C, Collins N, Paun A, Salcedo R, O'Shea JJ, Belkaid Y. Harrison OJ, et al. Among authors: smelkinson m. Science. 2019 Jan 4;363(6422):eaat6280. doi: 10.1126/science.aat6280. Epub 2018 Dec 6. Science. 2019. PMID: 30523076 Free PMC article.
Mg2+ regulation of kinase signaling and immune function.
Kanellopoulou C, George AB, Masutani E, Cannons JL, Ravell JC, Yamamoto TN, Smelkinson MG, Jiang PD, Matsuda-Lennikov M, Reilley J, Handon R, Lee PH, Miller JR, Restifo NP, Zheng L, Schwartzberg PL, Young M, Lenardo MJ. Kanellopoulou C, et al. Among authors: smelkinson mg. J Exp Med. 2019 Aug 5;216(8):1828-1842. doi: 10.1084/jem.20181970. Epub 2019 Jun 13. J Exp Med. 2019. PMID: 31196981 Free PMC article.
Emergence of Polyfunctional Cytotoxic CD4+ T Cells in Mycobacterium avium Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-Infected Patients.
Hsu DC, Breglio KF, Pei L, Wong CS, Andrade BB, Sheikh V, Smelkinson M, Petrovas C, Rupert A, Gil-Santana L, Zelazny A, Holland SM, Olivier K, Barber D, Sereti I. Hsu DC, et al. Among authors: smelkinson m. Clin Infect Dis. 2018 Jul 18;67(3):437-446. doi: 10.1093/cid/ciy016. Clin Infect Dis. 2018. PMID: 29538651 Free PMC article.
Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation.
Austin JW, Buckner CM, Kardava L, Wang W, Zhang X, Melson VA, Swanson RG, Martins AJ, Zhou JQ, Hoehn KB, Fisk JN, Dimopoulos Y, Chassiakos A, O'Dell S, Smelkinson MG, Seamon CA, Kwan RW, Sneller MC, Pittaluga S, Doria-Rose NA, McDermott A, Li Y, Chun TW, Kleinstein SH, Tsang JS, Petrovas C, Moir S. Austin JW, et al. Among authors: smelkinson mg. Sci Transl Med. 2019 Nov 27;11(520):eaax0904. doi: 10.1126/scitranslmed.aax0904. Sci Transl Med. 2019. PMID: 31776286 Free PMC article.
Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function.
Sampaio EP, Ding L, Rose SR, Cruz P, Hsu AP, Kashyap A, Rosen LB, Smelkinson M, Tavella TA, Ferre EMN, Wierman MK, Zerbe CS, Lionakis MS, Holland SM. Sampaio EP, et al. Among authors: smelkinson m. J Allergy Clin Immunol. 2018 May;141(5):1844-1853.e2. doi: 10.1016/j.jaci.2017.07.027. Epub 2017 Aug 30. J Allergy Clin Immunol. 2018. PMID: 28859974 Free PMC article.
Simian Immunodeficiency Virus-Infected Memory CD4+ T Cells Infiltrate to the Site of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS.
Lee CA, Beasley E, Sundar K, Smelkinson M, Vinton C, Deleage C, Matsuda K, Wu F, Estes JD, Lafont BAP, Brenchley JM, Hirsch VM. Lee CA, et al. Among authors: smelkinson m. mBio. 2020 Apr 21;11(2):e00602-20. doi: 10.1128/mBio.00602-20. mBio. 2020. PMID: 32317323 Free PMC article.
White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection.
Han SJ, Glatman Zaretsky A, Andrade-Oliveira V, Collins N, Dzutsev A, Shaik J, Morais da Fonseca D, Harrison OJ, Tamoutounour S, Byrd AL, Smelkinson M, Bouladoux N, Bliska JB, Brenchley JM, Brodsky IE, Belkaid Y. Han SJ, et al. Among authors: smelkinson m. Immunity. 2017 Dec 19;47(6):1154-1168.e6. doi: 10.1016/j.immuni.2017.11.009. Epub 2017 Dec 5. Immunity. 2017. PMID: 29221731 Free PMC article.
Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.
Linehan JL, Harrison OJ, Han SJ, Byrd AL, Vujkovic-Cvijin I, Villarino AV, Sen SK, Shaik J, Smelkinson M, Tamoutounour S, Collins N, Bouladoux N, Dzutsev A, Rosshart SP, Arbuckle JH, Wang CR, Kristie TM, Rehermann B, Trinchieri G, Brenchley JM, O'Shea JJ, Belkaid Y. Linehan JL, et al. Among authors: smelkinson m. Cell. 2018 Feb 8;172(4):784-796.e18. doi: 10.1016/j.cell.2017.12.033. Epub 2018 Jan 18. Cell. 2018. PMID: 29358051 Free PMC article.
Immunity to commensal skin fungi promotes psoriasiform skin inflammation.
Hurabielle C, Link VM, Bouladoux N, Han SJ, Merrill ED, Lightfoot YL, Seto N, Bleck CKE, Smelkinson M, Harrison OJ, Linehan JL, Tamoutounour S, Lionakis MS, Kaplan MJ, Nakajima S, Belkaid Y. Hurabielle C, et al. Among authors: smelkinson m. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16465-16474. doi: 10.1073/pnas.2003022117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601220 Free PMC article.
44 results