Teh JLF - Search Results

1

Activation of CD8⁺ T Cells Contributes to Antitumor Effects of CDK4/6 Inhibitors plus MEK Inhibitors.

Teh JLF, Erkes DA, Cheng PF, Tiago M, Wilski NA, Field CO, Chervoneva I, Levesque MP, Xu X, Dummer R, Aplin AE. Teh JLF, et al. Cancer Immunol Res. 2020 Sep;8(9):1114-1121. doi: 10.1158/2326-6066.CIR-19-0743. Epub 2020 Jul 13. Cancer Immunol Res. 2020. PMID: 32661093 Free PMC article.

2

An In Vivo Reporter to Quantitatively and Temporally Analyze the Effects of CDK4/6 Inhibitor-Based Therapies in Melanoma.

Teh JL, Purwin TJ, Greenawalt EJ, Chervoneva I, Goldberg A, Davies MA, Aplin AE. Teh JL, et al. Cancer Res. 2016 Sep 15;76(18):5455-66. doi: 10.1158/0008-5472.CAN-15-3384. Epub 2016 Aug 3. Cancer Res. 2016. PMID: 27488531 Free PMC article.

3

In Vivo E2F Reporting Reveals Efficacious Schedules of MEK1/2-CDK4/6 Targeting and mTOR-S6 Resistance Mechanisms.

Teh JLF, Cheng PF, Purwin TJ, Nikbakht N, Patel P, Chervoneva I, Ertel A, Fortina PM, Kleiber I, HooKim K, Davies MA, Kwong LN, Levesque MP, Dummer R, Aplin AE. Teh JLF, et al. Cancer Discov. 2018 May;8(5):568-581. doi: 10.1158/2159-8290.CD-17-0699. Epub 2018 Mar 1. Cancer Discov. 2018. PMID: 29496664 Free PMC article.

4

A Preexisting Rare PIK3CA^E545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling.

Romano G, Chen PL, Song P, McQuade JL, Liang RJ, Liu M, Roh W, Duose DY, Carapeto FCL, Li J, Teh JLF, Aplin AE, Chen M, Zhang J, Lazar AJ, Davies MA, Futreal PA, Amaria RN, Zhang DY, Wargo JA, Kwong LN. Romano G, et al. Among authors: teh jlf. Cancer Discov. 2018 May;8(5):556-567. doi: 10.1158/2159-8290.CD-17-0745. Epub 2018 Mar 1. Cancer Discov. 2018. PMID: 29496665 Free PMC article.

5

Playing the Melanoma Endgame.

Teh JLF, Aplin AE. Teh JLF, et al. Clin Cancer Res. 2018 Oct 1;24(19):4629-4630. doi: 10.1158/1078-0432.CCR-18-0989. Epub 2018 May 16. Clin Cancer Res. 2018. PMID: 29769205 Free PMC article.

6

Arrested Developments: CDK4/6 Inhibitor Resistance and Alterations in the Tumor Immune Microenvironment.

Teh JLF, Aplin AE. Teh JLF, et al. Clin Cancer Res. 2019 Feb 1;25(3):921-927. doi: 10.1158/1078-0432.CCR-18-1967. Epub 2018 Oct 4. Clin Cancer Res. 2019. PMID: 30287548 Free PMC article. Review.

7

Correction: In Vivo E2F Reporting Reveals Efficacious Schedules of MEK1/2-CDK4/6 Targeting and mTOR-S6 Resistance Mechanisms.

Teh JLF, Cheng PF, Purwin TJ, Nikbakht N, Patel P, Chervoneva I, Ertel A, Fortina PM, Kleiber I, HooKim K, Davies MA, Kwong LN, Levesque MP, Dummer R, Aplin AE. Teh JLF, et al. Cancer Discov. 2018 Dec;8(12):1654. doi: 10.1158/2159-8290.CD-18-1291. Cancer Discov. 2018. PMID: 30510016 No abstract available.

8

Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma.

Chua V, Orloff M, Teh JL, Sugase T, Liao C, Purwin TJ, Lam BQ, Terai M, Ambrosini G, Carvajal RD, Schwartz G, Sato T, Aplin AE. Chua V, et al. EMBO Mol Med. 2019 Feb;11(2):e9081. doi: 10.15252/emmm.201809081. EMBO Mol Med. 2019. PMID: 30610113 Free PMC article.

9

Targeting PHGDH Upregulation Reduces Glutathione Levels and Resensitizes Resistant NRAS-Mutant Melanoma to MAPK Kinase Inhibition.

Nguyen MQ, Teh JLF, Purwin TJ, Chervoneva I, Davies MA, Nathanson KL, Cheng PF, Levesque MP, Dummer R, Aplin AE. Nguyen MQ, et al. Among authors: teh jlf. J Invest Dermatol. 2020 Nov;140(11):2242-2252.e7. doi: 10.1016/j.jid.2020.02.047. Epub 2020 May 7. J Invest Dermatol. 2020. PMID: 32389536 Free PMC article.

10

Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma.

Teh JLF, Purwin TJ, Han A, Chua V, Patel P, Baqai U, Liao C, Bechtel N, Sato T, Davies MA, Aguirre-Ghiso J, Aplin AE. Teh JLF, et al. Mol Cancer Ther. 2020 Aug;19(8):1719-1726. doi: 10.1158/1535-7163.MCT-19-1016. Epub 2020 May 19. Mol Cancer Ther. 2020. PMID: 32430489 Free PMC article.

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