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A cocrystal structure of dengue capsid protein in complex of inhibitor.
Xia H, Xie X, Zou J, Noble CG, Russell WK, Holthauzen LMF, Choi KH, White MA, Shi PY. Xia H, et al. Among authors: shi py. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17992-18001. doi: 10.1073/pnas.2003056117. Epub 2020 Jul 15. Proc Natl Acad Sci U S A. 2020. PMID: 32669438 Free PMC article.
An adenosine nucleoside inhibitor of dengue virus.
Yin Z, Chen YL, Schul W, Wang QY, Gu F, Duraiswamy J, Kondreddi RR, Niyomrattanakit P, Lakshminarayana SB, Goh A, Xu HY, Liu W, Liu B, Lim JY, Ng CY, Qing M, Lim CC, Yip A, Wang G, Chan WL, Tan HP, Lin K, Zhang B, Zou G, Bernard KA, Garrett C, Beltz K, Dong M, Weaver M, He H, Pichota A, Dartois V, Keller TH, Shi PY. Yin Z, et al. Among authors: shi py. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20435-9. doi: 10.1073/pnas.0907010106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918064 Free PMC article.
Strategies for development of Dengue virus inhibitors.
Noble CG, Chen YL, Dong H, Gu F, Lim SP, Schul W, Wang QY, Shi PY. Noble CG, et al. Among authors: shi py. Antiviral Res. 2010 Mar;85(3):450-62. doi: 10.1016/j.antiviral.2009.12.011. Epub 2010 Jan 8. Antiviral Res. 2010. PMID: 20060421 Review.
Small molecule inhibitors that selectively block dengue virus methyltransferase.
Lim SP, Sonntag LS, Noble C, Nilar SH, Ng RH, Zou G, Monaghan P, Chung KY, Dong H, Liu B, Bodenreider C, Lee G, Ding M, Chan WL, Wang G, Jian YL, Chao AT, Lescar J, Yin Z, Vedananda TR, Keller TH, Shi PY. Lim SP, et al. Among authors: shi py. J Biol Chem. 2011 Feb 25;286(8):6233-40. doi: 10.1074/jbc.M110.179184. Epub 2010 Dec 8. J Biol Chem. 2011. PMID: 21147775 Free PMC article.
A translation inhibitor that suppresses dengue virus in vitro and in vivo.
Wang QY, Kondreddi RR, Xie X, Rao R, Nilar S, Xu HY, Qing M, Chang D, Dong H, Yokokawa F, Lakshminarayana SB, Goh A, Schul W, Kramer L, Keller TH, Shi PY. Wang QY, et al. Among authors: shi py. Antimicrob Agents Chemother. 2011 Sep;55(9):4072-80. doi: 10.1128/AAC.00620-11. Epub 2011 Jul 5. Antimicrob Agents Chemother. 2011. PMID: 21730119 Free PMC article.
Inhibition of dengue virus by targeting viral NS4B protein.
Xie X, Wang QY, Xu HY, Qing M, Kramer L, Yuan Z, Shi PY. Xie X, et al. Among authors: shi py. J Virol. 2011 Nov;85(21):11183-95. doi: 10.1128/JVI.05468-11. Epub 2011 Aug 24. J Virol. 2011. PMID: 21865382 Free PMC article.
474 results