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LEFTY1 Is a Dual-SMAD Inhibitor that Promotes Mammary Progenitor Growth and Tumorigenesis.
Cell Stem Cell. 2020 Aug 6;27(2):284-299.e8. doi: 10.1016/j.stem.2020.06.017. Epub 2020 Jul 20.
Cell Stem Cell. 2020.
PMID: 32693087
Free article.
In vivo genome-editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis.
Heitink L, Whittle JR, Vaillant F, Capaldo BD, Dekkers JF, Dawson CA, Milevskiy MJG, Surgenor E, Tsai M, Chen HR, Christie M, Chen Y, Smyth GK, Herold MJ, Strasser A, Lindeman GJ, Visvader JE.
Heitink L, et al.
Mol Oncol. 2022 Mar;16(5):1119-1131. doi: 10.1002/1878-0261.13179. Epub 2022 Jan 26.
Mol Oncol. 2022.
PMID: 35000262
Free PMC article.
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Persistent repair intermediates induce senescence.
Feringa FM, Raaijmakers JA, Hadders MA, Vaarting C, Macurek L, Heitink L, Krenning L, Medema RH.
Feringa FM, et al.
Nat Commun. 2018 Sep 25;9(1):3923. doi: 10.1038/s41467-018-06308-9.
Nat Commun. 2018.
PMID: 30254262
Free PMC article.
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