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Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics.
Gilchuk P, Bombardi RG, Erasmus JH, Tan Q, Nargi R, Soto C, Abbink P, Suscovich TJ, Durnell LA, Khandhar A, Archer J, Liang J, Fouch ME, Davidson E, Doranz BJ, Jones T, Larson E, Ertel S, Granger B, Fuerte-Stone J, Roy V, Broge T, Linnekin TC, Linde CH, Gorman MJ, Nkolola J, Alter G, Reed SG, Barouch DH, Diamond MS, Crowe JE Jr, Van Hoeven N, Thackray LB, Carnahan RH. Gilchuk P, et al. Among authors: roy v. Nat Biomed Eng. 2020 Nov;4(11):1030-1043. doi: 10.1038/s41551-020-0594-x. Epub 2020 Aug 3. Nat Biomed Eng. 2020. PMID: 32747832 Free PMC article.
Survivors of Ebola Virus Disease Develop Polyfunctional Antibody Responses.
Gunn BM, Roy V, Karim MM, Hartnett JN, Suscovich TJ, Goba A, Momoh M, Sandi JD, Kanneh L, Andersen KG, Shaffer JG, Schieffelin JS, Garry RF, Grant DS, Alter G. Gunn BM, et al. Among authors: roy v. J Infect Dis. 2020 Jan 1;221(1):156-161. doi: 10.1093/infdis/jiz364. J Infect Dis. 2020. PMID: 31301137 Free PMC article.
Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality.
Maciejewski S, Ruckwardt TJ, Morabito KM, Foreman BM, Burgomaster KE, Gordon DN, Pelc RS, DeMaso CR, Ko SY, Fisher BE, Yang ES, Nair D, Foulds KE, Todd JP, Kong WP, Roy V, Aleshnick M, Speer SD, Bourne N, Barrett AD, Nason MC, Roederer M, Gaudinski MR, Chen GL, Dowd KA, Ledgerwood JE, Alter G, Mascola JR, Graham BS, Pierson TC. Maciejewski S, et al. Among authors: roy v. Sci Transl Med. 2020 Jun 10;12(547):eaaw9066. doi: 10.1126/scitranslmed.aaw9066. Sci Transl Med. 2020. PMID: 32522807
SARS-CoV-2-specific ELISA development.
Roy V, Fischinger S, Atyeo C, Slein M, Loos C, Balazs A, Luedemann C, Astudillo MG, Yang D, Wesemann DR, Charles R, Lafrate AJ, Feldman J, Hauser B, Caradonna T, Miller TE, Murali MR, Baden L, Nilles E, Ryan E, Lauffenburger D, Beltran WG, Alter G. Roy V, et al. J Immunol Methods. 2020 Sep-Oct;484-485:112832. doi: 10.1016/j.jim.2020.112832. Epub 2020 Aug 8. J Immunol Methods. 2020. PMID: 32780998 Free PMC article.
A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus.
Gunn BM, Lu R, Slein MD, Ilinykh PA, Huang K, Atyeo C, Schendel SL, Kim J, Cain C, Roy V, Suscovich TJ, Takada A, Halfmann PJ, Kawaoka Y, Pauthner MG, Momoh M, Goba A, Kanneh L, Andersen KG, Schieffelin JS, Grant D, Garry RF, Saphire EO, Bukreyev A, Alter G. Gunn BM, et al. Among authors: roy v. Immunity. 2021 Apr 13;54(4):815-828.e5. doi: 10.1016/j.immuni.2021.03.009. Immunity. 2021. PMID: 33852832 Free PMC article.
Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress.
Williamson LE, Reeder KM, Bailey K, Tran MH, Roy V, Fouch ME, Kose N, Trivette A, Nargi RS, Winkler ES, Kim AS, Gainza C, Rodriguez J, Armstrong E, Sutton RE, Reidy J, Carnahan RH, McDonald WH, Schoeder CT, Klimstra WB, Davidson E, Doranz BJ, Alter G, Meiler J, Schey KL, Julander JG, Diamond MS, Crowe JE Jr. Williamson LE, et al. Among authors: roy v. Cell. 2021 Aug 19;184(17):4430-4446.e22. doi: 10.1016/j.cell.2021.07.033. Cell. 2021. PMID: 34416147 Free PMC article.
Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges.
Lakhashe SK, Amacker M, Hariraju D, Vyas HK, Morrison KS, Weiner JA, Ackerman ME, Roy V, Alter G, Ferrari G, Montefiori DC, Tomaras GD, Sawant S, Yates NL, Gast C, Fleury S, Ruprecht RM. Lakhashe SK, et al. Among authors: roy v. Front Immunol. 2022 Feb 22;13:788619. doi: 10.3389/fimmu.2022.788619. eCollection 2022. Front Immunol. 2022. PMID: 35273592 Free PMC article.
651 results