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Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics.
Gilchuk P, Bombardi RG, Erasmus JH, Tan Q, Nargi R, Soto C, Abbink P, Suscovich TJ, Durnell LA, Khandhar A, Archer J, Liang J, Fouch ME, Davidson E, Doranz BJ, Jones T, Larson E, Ertel S, Granger B, Fuerte-Stone J, Roy V, Broge T, Linnekin TC, Linde CH, Gorman MJ, Nkolola J, Alter G, Reed SG, Barouch DH, Diamond MS, Crowe JE Jr, Van Hoeven N, Thackray LB, Carnahan RH. Gilchuk P, et al. Among authors: thackray lb. Nat Biomed Eng. 2020 Nov;4(11):1030-1043. doi: 10.1038/s41551-020-0594-x. Epub 2020 Aug 3. Nat Biomed Eng. 2020. PMID: 32747832 Free PMC article.
Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma.
Hwang S, Maloney NS, Bruinsma MW, Goel G, Duan E, Zhang L, Shrestha B, Diamond MS, Dani A, Sosnovtsev SV, Green KY, Lopez-Otin C, Xavier RJ, Thackray LB, Virgin HW. Hwang S, et al. Among authors: thackray lb. Cell Host Microbe. 2012 Apr 19;11(4):397-409. doi: 10.1016/j.chom.2012.03.002. Cell Host Microbe. 2012. PMID: 22520467 Free PMC article.
Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome.
Handley SA, Thackray LB, Zhao G, Presti R, Miller AD, Droit L, Abbink P, Maxfield LF, Kambal A, Duan E, Stanley K, Kramer J, Macri SC, Permar SR, Schmitz JE, Mansfield K, Brenchley JM, Veazey RS, Stappenbeck TS, Wang D, Barouch DH, Virgin HW. Handley SA, et al. Among authors: thackray lb. Cell. 2012 Oct 12;151(2):253-66. doi: 10.1016/j.cell.2012.09.024. Cell. 2012. PMID: 23063120 Free PMC article.
Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins.
Quiroz JA, Malonis RJ, Thackray LB, Cohen CA, Pallesen J, Jangra RK, Brown RS, Hofmann D, Holtsberg FW, Shulenin S, Nyakatura EK, Durnell LA, Rayannavar V, Daily JP, Ward AB, Aman MJ, Dye JM, Chandran K, Diamond MS, Kielian M, Lai JR. Quiroz JA, et al. Among authors: thackray lb. PLoS Pathog. 2019 Nov 7;15(11):e1008061. doi: 10.1371/journal.ppat.1008061. eCollection 2019 Nov. PLoS Pathog. 2019. PMID: 31697791 Free PMC article.
Immune correlates of tuberculosis disease and risk translate across species.
Ahmed M, Thirunavukkarasu S, Rosa BA, Thomas KA, Das S, Rangel-Moreno J, Lu L, Mehra S, Mbandi SK, Thackray LB, Diamond MS, Murphy KM, Means T, Martin J, Kaushal D, Scriba TJ, Mitreva M, Khader SA. Ahmed M, et al. Among authors: thackray lb. Sci Transl Med. 2020 Jan 29;12(528):eaay0233. doi: 10.1126/scitranslmed.aay0233. Sci Transl Med. 2020. PMID: 31996462 Free PMC article.
70 results