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Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes.
Affandi AJ, Grabowska J, Olesek K, Lopez Venegas M, Barbaria A, Rodríguez E, Mulder PPG, Pijffers HJ, Ambrosini M, Kalay H, O'Toole T, Zwart ES, Kazemier G, Nazmi K, Bikker FJ, Stöckl J, van den Eertwegh AJM, de Gruijl TD, Storm G, van Kooyk Y, den Haan JMM. Affandi AJ, et al. Among authors: grabowska j. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27528-27539. doi: 10.1073/pnas.2006186117. Epub 2020 Oct 16. Proc Natl Acad Sci U S A. 2020. PMID: 33067394 Free PMC article.
Optimization of Liposomes for Antigen Targeting to Splenic CD169+ Macrophages.
Nijen Twilhaar MK, Czentner L, Grabowska J, Affandi AJ, Lau CYJ, Olesek K, Kalay H, van Nostrum CF, van Kooyk Y, Storm G, Haan JMMD. Nijen Twilhaar MK, et al. Among authors: grabowska j. Pharmaceutics. 2020 Nov 25;12(12):1138. doi: 10.3390/pharmaceutics12121138. Pharmaceutics. 2020. PMID: 33255564 Free PMC article.
CD169 Defines Activated CD14+ Monocytes With Enhanced CD8+ T Cell Activation Capacity.
Affandi AJ, Olesek K, Grabowska J, Nijen Twilhaar MK, Rodríguez E, Saris A, Zwart ES, Nossent EJ, Kalay H, de Kok M, Kazemier G, Stöckl J, van den Eertwegh AJM, de Gruijl TD, Garcia-Vallejo JJ, Storm G, van Kooyk Y, den Haan JMM. Affandi AJ, et al. Among authors: grabowska j. Front Immunol. 2021 Jul 28;12:697840. doi: 10.3389/fimmu.2021.697840. eCollection 2021. Front Immunol. 2021. PMID: 34394090 Free PMC article.
Liposome induction of CD8+ T cell responses depends on CD169+ macrophages and Batf3-dependent dendritic cells and is enhanced by GM3 inclusion.
Grabowska J, Affandi AJ, van Dinther D, Nijen Twilhaar MK, Olesek K, Hoogterp L, Ambrosini M, Heijnen DAM, Klaase L, Hidalgo A, Asano K, Crocker PR, Storm G, van Kooyk Y, den Haan JMM. Grabowska J, et al. J Control Release. 2021 Mar 10;331:309-320. doi: 10.1016/j.jconrel.2021.01.029. Epub 2021 Jan 22. J Control Release. 2021. PMID: 33493613 Free article.
Incorporation of Toll-Like Receptor Ligands and Inflammasome Stimuli in GM3 Liposomes to Induce Dendritic Cell Maturation and T Cell Responses.
Nijen Twilhaar MK, Czentner L, Bouma RG, Olesek K, Grabowska J, Wang AZ, Affandi AJ, Belt SC, Kalay H, van Nostrum CF, van Kooyk Y, Storm G, den Haan JMM. Nijen Twilhaar MK, et al. Among authors: grabowska j. Front Immunol. 2022 Feb 18;13:842241. doi: 10.3389/fimmu.2022.842241. eCollection 2022. Front Immunol. 2022. PMID: 35251040 Free PMC article.
51 results