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The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Ghorani E, Reading JL, Henry JY, Massy MR, Rosenthal R, Turati V, Joshi K, Furness AJS, Ben Aissa A, Saini SK, Ramskov S, Georgiou A, Sunderland MW, Wong YNS, Mucha MV, Day W, Galvez-Cancino F, Becker PD, Uddin I, Oakes T, Ismail M, Ronel T, Woolston A, Jamal-Hanjani M, Veeriah S, Birkbak NJ, Wilson GA, Litchfield K, Conde L, Guerra-Assunção JA, Blighe K, Biswas D, Salgado R, Lund T, Bakir MA, Moore DA, Hiley CT, Loi S, Sun Y, Yuan Y, AbdulJabbar K, Turajilic S, Herrero J, Enver T, Hadrup SR, Hackshaw A, Peggs KS, McGranahan N, Chain B; TRACERx Consortium; Swanton C, Quezada SA. Ghorani E, et al. Among authors: birkbak nj. Nat Cancer. 2020 May;1(5):546-561. doi: 10.1038/s43018-020-0066-y. Epub 2020 May 22. Nat Cancer. 2020. PMID: 32803172 Free PMC article.
Impact of Whole Genome Doubling on Detection of Circulating Tumor DNA in Colorectal Cancer.
Kabel J, Henriksen TV, Demuth C, Frydendahl A, Rasmussen MH, Nors J, Birkbak NJ, Madsen AH, Løve US, Andersen PV, Kolbro T, Monti A, Thorlacius-Ussing O, Gögenur M, Kildsig J, Schlesinger NH, Bondeven P, Iversen LH, Gotschalck KA, Andersen CL. Kabel J, et al. Among authors: birkbak nj. Cancers (Basel). 2023 Feb 10;15(4):1136. doi: 10.3390/cancers15041136. Cancers (Basel). 2023. PMID: 36831479 Free PMC article.
Chromosomal instability confers intrinsic multidrug resistance.
Lee AJ, Endesfelder D, Rowan AJ, Walther A, Birkbak NJ, Futreal PA, Downward J, Szallasi Z, Tomlinson IP, Howell M, Kschischo M, Swanton C. Lee AJ, et al. Among authors: birkbak nj. Cancer Res. 2011 Mar 1;71(5):1858-70. doi: 10.1158/0008-5472.CAN-10-3604. Cancer Res. 2011. PMID: 21363922 Free PMC article.
Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer.
Roylance R, Endesfelder D, Gorman P, Burrell RA, Sander J, Tomlinson I, Hanby AM, Speirs V, Richardson AL, Birkbak NJ, Eklund AC, Downward J, Kschischo M, Szallasi Z, Swanton C. Roylance R, et al. Among authors: birkbak nj. Cancer Epidemiol Biomarkers Prev. 2011 Oct;20(10):2183-94. doi: 10.1158/1055-9965.EPI-11-0343. Epub 2011 Jul 22. Cancer Epidemiol Biomarkers Prev. 2011. PMID: 21784954 Free PMC article.
CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction.
Lee AJ, Roylance R, Sander J, Gorman P, Endesfelder D, Kschischo M, Jones NP, East P, Nicke B, Spassieva S, Obeid LM, Birkbak NJ, Szallasi Z, McKnight NC, Rowan AJ, Speirs V, Hanby AM, Downward J, Tooze SA, Swanton C. Lee AJ, et al. Among authors: birkbak nj. J Pathol. 2012 Feb;226(3):482-94. doi: 10.1002/path.2998. Epub 2011 Oct 19. J Pathol. 2012. PMID: 21953249
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