Garcia KC - Search Results

1

Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo.

Miao Y, Ha A, de Lau W, Yuki K, Santos AJM, You C, Geurts MH, Puschhof J, Pleguezuelos-Manzano C, Peng WC, Senlice R, Piani C, Buikema JW, Gbenedio OM, Vallon M, Yuan J, de Haan S, Hemrika W, Rösch K, Dang LT, Baker D, Ott M, Depeille P, Wu SM, Drost J, Nusse R, Roose JP, Piehler J, Boj SF, Janda CY, Clevers H, Kuo CJ, Garcia KC. Miao Y, et al. Among authors: garcia kc. Cell Stem Cell. 2020 Nov 5;27(5):840-851.e6. doi: 10.1016/j.stem.2020.07.020. Epub 2020 Aug 19. Cell Stem Cell. 2020. PMID: 32818433 Free PMC article.

2

Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130.

Boulanger MJ, Bankovich AJ, Kortemme T, Baker D, Garcia KC. Boulanger MJ, et al. Among authors: garcia kc. Mol Cell. 2003 Sep;12(3):577-89. doi: 10.1016/s1097-2765(03)00365-4. Mol Cell. 2003. PMID: 14527405 Free article.

3

Structural linkage between ligand discrimination and receptor activation by type I interferons.

Thomas C, Moraga I, Levin D, Krutzik PO, Podoplelova Y, Trejo A, Lee C, Yarden G, Vleck SE, Glenn JS, Nolan GP, Piehler J, Schreiber G, Garcia KC. Thomas C, et al. Among authors: garcia kc. Cell. 2011 Aug 19;146(4):621-32. doi: 10.1016/j.cell.2011.06.048. Cell. 2011. PMID: 21854986 Free PMC article.

4

Structural basis of Wnt recognition by Frizzled.

Janda CY, Waghray D, Levin AM, Thomas C, Garcia KC. Janda CY, et al. Among authors: garcia kc. Science. 2012 Jul 6;337(6090):59-64. doi: 10.1126/science.1222879. Epub 2012 May 31. Science. 2012. PMID: 22653731 Free PMC article.

5

Structural architecture and functional evolution of Wnts.

Bazan JF, Janda CY, Garcia KC. Bazan JF, et al. Among authors: garcia kc. Dev Cell. 2012 Aug 14;23(2):227-32. doi: 10.1016/j.devcel.2012.07.011. Dev Cell. 2012. PMID: 22898770 Free PMC article.

6

Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.

Piehler J, Thomas C, Garcia KC, Schreiber G. Piehler J, et al. Among authors: garcia kc. Immunol Rev. 2012 Nov;250(1):317-34. doi: 10.1111/imr.12001. Immunol Rev. 2012. PMID: 23046138 Free PMC article. Review.

7

Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands.

Moraga I, Wernig G, Wilmes S, Gryshkova V, Richter CP, Hong WJ, Sinha R, Guo F, Fabionar H, Wehrman TS, Krutzik P, Demharter S, Plo I, Weissman IL, Minary P, Majeti R, Constantinescu SN, Piehler J, Garcia KC. Moraga I, et al. Among authors: garcia kc. Cell. 2015 Mar 12;160(6):1196-208. doi: 10.1016/j.cell.2015.02.011. Epub 2015 Feb 26. Cell. 2015. PMID: 25728669 Free PMC article.

8

Wnt acylation and its functional implication in Wnt signalling regulation.

Janda CY, Garcia KC. Janda CY, et al. Among authors: garcia kc. Biochem Soc Trans. 2015 Apr;43(2):211-6. doi: 10.1042/BST20140249. Biochem Soc Trans. 2015. PMID: 25849919 Free PMC article. Review.

9

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.

Moraga I, Richter D, Wilmes S, Winkelmann H, Jude K, Thomas C, Suhoski MM, Engleman EG, Piehler J, Garcia KC. Moraga I, et al. Among authors: garcia kc. Sci Signal. 2015 Nov 10;8(402):ra114. doi: 10.1126/scisignal.aab2677. Sci Signal. 2015. PMID: 26554818 Free PMC article.

10

Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling.

You C, Marquez-Lago TT, Richter CP, Wilmes S, Moraga I, Garcia KC, Leier A, Piehler J. You C, et al. Among authors: garcia kc. Sci Adv. 2016 Dec 2;2(12):e1600452. doi: 10.1126/sciadv.1600452. eCollection 2016 Dec. Sci Adv. 2016. PMID: 27957535 Free PMC article.

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