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Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Klemm T, Ebert G, Calleja DJ, Allison CC, Richardson LW, Bernardini JP, Lu BG, Kuchel NW, Grohmann C, Shibata Y, Gan ZY, Cooney JP, Doerflinger M, Au AE, Blackmore TR, van der Heden van Noort GJ, Geurink PP, Ovaa H, Newman J, Riboldi-Tunnicliffe A, Czabotar PE, Mitchell JP, Feltham R, Lechtenberg BC, Lowes KN, Dewson G, Pellegrini M, Lessene G, Komander D. Klemm T, et al. Among authors: doerflinger m. EMBO J. 2020 Sep 15;39(18):e106275. doi: 10.15252/embj.2020106275. Epub 2020 Aug 26. EMBO J. 2020. PMID: 32845033 Free PMC article.
i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4.
Griffiths K, Dolezal O, Cao B, Nilsson SK, See HB, Pfleger KDG, Roche M, Gorry PR, Pow A, Viduka K, Lim K, Lu BGC, Chang DHC, Murray-Rust T, Kvansakul M, Perugini MA, Dogovski C, Doerflinger M, Zhang Y, Parisi K, Casey JL, Nuttall SD, Foley M. Griffiths K, et al. Among authors: doerflinger m. J Biol Chem. 2016 Jun 10;291(24):12641-12657. doi: 10.1074/jbc.M116.721050. Epub 2016 Apr 1. J Biol Chem. 2016. PMID: 27036939 Free PMC article.
Targeting the Extrinsic Pathway of Hepatocyte Apoptosis Promotes Clearance of Plasmodium Liver Infection.
Ebert G, Lopaticki S, O'Neill MT, Steel RWJ, Doerflinger M, Rajasekaran P, Yang ASP, Erickson S, Ioannidis L, Arandjelovic P, Mackiewicz L, Allison C, Silke J, Pellegrini M, Boddey JA. Ebert G, et al. Among authors: doerflinger m. Cell Rep. 2020 Mar 31;30(13):4343-4354.e4. doi: 10.1016/j.celrep.2020.03.032. Cell Rep. 2020. PMID: 32234472 Free article.
Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection.
Doerflinger M, Deng Y, Whitney P, Salvamoser R, Engel S, Kueh AJ, Tai L, Bachem A, Gressier E, Geoghegan ND, Wilcox S, Rogers KL, Garnham AL, Dengler MA, Bader SM, Ebert G, Pearson JS, De Nardo D, Wang N, Yang C, Pereira M, Bryant CE, Strugnell RA, Vince JE, Pellegrini M, Strasser A, Bedoui S, Herold MJ. Doerflinger M, et al. Immunity. 2020 Sep 15;53(3):533-547.e7. doi: 10.1016/j.immuni.2020.07.004. Epub 2020 Jul 30. Immunity. 2020. PMID: 32735843 Free PMC article.
The role of MKK4 in T-cell development and immunity to viral infections.
Preston SP, Doerflinger M, Scott HW, Allison CC, Horton M, Cooney J, Pellegrini M. Preston SP, et al. Among authors: doerflinger m. Immunol Cell Biol. 2021 Apr;99(4):428-435. doi: 10.1111/imcb.12426. Epub 2020 Dec 8. Immunol Cell Biol. 2021. PMID: 33175451 Free PMC article.
48 results