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Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Klemm T, Ebert G, Calleja DJ, Allison CC, Richardson LW, Bernardini JP, Lu BG, Kuchel NW, Grohmann C, Shibata Y, Gan ZY, Cooney JP, Doerflinger M, Au AE, Blackmore TR, van der Heden van Noort GJ, Geurink PP, Ovaa H, Newman J, Riboldi-Tunnicliffe A, Czabotar PE, Mitchell JP, Feltham R, Lechtenberg BC, Lowes KN, Dewson G, Pellegrini M, Lessene G, Komander D. Klemm T, et al. Among authors: ebert g. EMBO J. 2020 Sep 15;39(18):e106275. doi: 10.15252/embj.2020106275. Epub 2020 Aug 26. EMBO J. 2020. PMID: 32845033 Free PMC article.
ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system.
Lin AE, Ebert G, Ow Y, Preston SP, Toe JG, Cooney JP, Scott HW, Sasaki M, Saibil SD, Dissanayake D, Kim RH, Wakeham A, You-Ten A, Shahinian A, Duncan G, Silvester J, Ohashi PS, Mak TW, Pellegrini M. Lin AE, et al. Among authors: ebert g. Nat Immunol. 2013 Jan;14(1):27-33. doi: 10.1038/ni.2478. Epub 2012 Nov 25. Nat Immunol. 2013. PMID: 23179078
Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus.
Ebert G, Preston S, Allison C, Cooney J, Toe JG, Stutz MD, Ojaimi S, Scott HW, Baschuk N, Nachbur U, Torresi J, Chin R, Colledge D, Li X, Warner N, Revill P, Bowden S, Silke J, Begley CG, Pellegrini M. Ebert G, et al. Proc Natl Acad Sci U S A. 2015 May 5;112(18):5797-802. doi: 10.1073/pnas.1502390112. Epub 2015 Apr 20. Proc Natl Acad Sci U S A. 2015. PMID: 25902529 Free PMC article.
Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis.
Ebert G, Allison C, Preston S, Cooney J, Toe JG, Stutz MD, Ojaimi S, Baschuk N, Nachbur U, Torresi J, Silke J, Begley CG, Pellegrini M. Ebert G, et al. Proc Natl Acad Sci U S A. 2015 May 5;112(18):5803-8. doi: 10.1073/pnas.1502400112. Epub 2015 Apr 20. Proc Natl Acad Sci U S A. 2015. PMID: 25902530 Free PMC article.
CRISPR/Cas9-The ultimate weapon to battle infectious diseases?
Doerflinger M, Forsyth W, Ebert G, Pellegrini M, Herold MJ. Doerflinger M, et al. Among authors: ebert g. Cell Microbiol. 2017 Feb;19(2). doi: 10.1111/cmi.12693. Epub 2016 Dec 6. Cell Microbiol. 2017. PMID: 27860197 Review.
The role of tumour necrosis factor in hepatitis B infection: Jekyll and Hyde.
Valaydon Z, Pellegrini M, Thompson A, Desmond P, Revill P, Ebert G. Valaydon Z, et al. Among authors: ebert g. Clin Transl Immunology. 2016 Dec 9;5(12):e115. doi: 10.1038/cti.2016.68. eCollection 2016 Dec. Clin Transl Immunology. 2016. PMID: 28090316 Free PMC article. Review.
Vaccines licensed and in clinical trials for the prevention of dengue.
Torresi J, Ebert G, Pellegrini M. Torresi J, et al. Among authors: ebert g. Hum Vaccin Immunother. 2017 May 4;13(5):1059-1072. doi: 10.1080/21645515.2016.1261770. Epub 2017 Feb 14. Hum Vaccin Immunother. 2017. PMID: 28281864 Free PMC article. Review.
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