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Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Klemm T, Ebert G, Calleja DJ, Allison CC, Richardson LW, Bernardini JP, Lu BG, Kuchel NW, Grohmann C, Shibata Y, Gan ZY, Cooney JP, Doerflinger M, Au AE, Blackmore TR, van der Heden van Noort GJ, Geurink PP, Ovaa H, Newman J, Riboldi-Tunnicliffe A, Czabotar PE, Mitchell JP, Feltham R, Lechtenberg BC, Lowes KN, Dewson G, Pellegrini M, Lessene G, Komander D. Klemm T, et al. Among authors: van der heden van noort gj. EMBO J. 2020 Sep 15;39(18):e106275. doi: 10.15252/embj.2020106275. Epub 2020 Aug 26. EMBO J. 2020. PMID: 32845033 Free PMC article.
Generation of the UFM1 Toolkit for Profiling UFM1-Specific Proteases and Ligases.
Witting KF, van der Heden van Noort GJ, Kofoed C, Talavera Ormeño C, El Atmioui D, Mulder MPC, Ovaa H. Witting KF, et al. Among authors: van der heden van noort gj. Angew Chem Int Ed Engl. 2018 Oct 22;57(43):14164-14168. doi: 10.1002/anie.201809232. Epub 2018 Oct 1. Angew Chem Int Ed Engl. 2018. PMID: 30188611 Free PMC article.
Profiling DUBs and Ubl-specific proteases with activity-based probes.
Geurink PP, van der Heden van Noort GJ, Mulder MPC, Knaap RCM, Kikkert M, Ovaa H. Geurink PP, et al. Among authors: van der heden van noort gj. Methods Enzymol. 2019;618:357-387. doi: 10.1016/bs.mie.2018.12.037. Epub 2019 Feb 14. Methods Enzymol. 2019. PMID: 30850060 Free PMC article.
Nedd8 hydrolysis by UCH proteases in Plasmodium parasites.
Karpiyevich M, Adjalley S, Mol M, Ascher DB, Mason B, van der Heden van Noort GJ, Laman H, Ovaa H, Lee MCS, Artavanis-Tsakonas K. Karpiyevich M, et al. Among authors: van der heden van noort gj. PLoS Pathog. 2019 Oct 28;15(10):e1008086. doi: 10.1371/journal.ppat.1008086. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31658303 Free PMC article.
51 results