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Inhibition of IRF5 hyperactivation protects from lupus onset and severity.
Song S, De S, Nelson V, Chopra S, LaPan M, Kampta K, Sun S, He M, Thompson CD, Li D, Shih T, Tan N, Al-Abed Y, Capitle E, Aranow C, Mackay M, Clapp WL, Barnes BJ. Song S, et al. Among authors: he m. J Clin Invest. 2020 Dec 1;130(12):6700-6717. doi: 10.1172/JCI120288. J Clin Invest. 2020. PMID: 32897883 Free PMC article. Clinical Trial.
Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice.
Hudson LK, Dancho ME, Li J, Bruchfeld JB, Ragab AA, He MM, Bragg M, Lenaghan D, Quinn MD, Fritz JR, Tanzi MV, Silverman HA, Hanes WM, Levine YA, Pavlov VA, Olofsson PS, Roth J, Al-Abed Y, Andersson U, Tracey KJ, Chavan SS. Hudson LK, et al. Among authors: he mm. Mol Med. 2016 Oct;22:585-596. doi: 10.2119/molmed.2016.00082. Epub 2016 Jun 10. Mol Med. 2016. PMID: 27341452 Free PMC article.
Amending HIV Drugs: A Novel Small-Molecule Approach To Target Lupus Anti-DNA Antibodies.
VanPatten S, Sun S, He M, Cheng KF, Altiti A, Papatheodorou A, Kowal C, Jeganathan V, Crawford JM, Bloom O, Volpe BT, Grant C, Meurice N, Coleman TR, Diamond B, Al-Abed Y. VanPatten S, et al. Among authors: he m. J Med Chem. 2016 Oct 13;59(19):8859-8867. doi: 10.1021/acs.jmedchem.6b00694. Epub 2016 Sep 20. J Med Chem. 2016. PMID: 27603688 Free PMC article.
C1q and HMGB1 reciprocally regulate human macrophage polarization.
Son M, Porat A, He M, Suurmond J, Santiago-Schwarz F, Andersson U, Coleman TR, Volpe BT, Tracey KJ, Al-Abed Y, Diamond B. Son M, et al. Among authors: he m. Blood. 2016 Nov 3;128(18):2218-2228. doi: 10.1182/blood-2016-05-719757. Epub 2016 Sep 28. Blood. 2016. PMID: 27683415 Free PMC article.
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