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Inhibition of IRF5 hyperactivation protects from lupus onset and severity.
J Clin Invest. 2020 Dec 1;130(12):6700-6717. doi: 10.1172/JCI120288.
J Clin Invest. 2020.
PMID: 32897883
Free PMC article.
Clinical Trial.
Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization.
Banga J, Srinivasan D, Sun CC, Thompson CD, Milletti F, Huang KS, Hamilton S, Song S, Hoffman AF, Qin YG, Matta B, LaPan M, Guo Q, Lu G, Li D, Qian H, Bolin DR, Liang L, Wartchow C, Qiu J, Downing M, Narula S, Fotouhi N, DeMartino JA, Tan SL, Chen G, Barnes BJ.
Banga J, et al. Among authors: lapan m.
Sci Adv. 2020 May 15;6(20):eaay1057. doi: 10.1126/sciadv.aay1057. eCollection 2020 May.
Sci Adv. 2020.
PMID: 32440537
Free PMC article.
Item in Clipboard
Identification of pan-cancer/testis genes and validation of therapeutic targeting in triple-negative breast cancer: Lin28a-based and Siglece-based vaccination induces antitumor immunity and inhibits metastasis.
Carter JA, Matta B, Battaglia J, Somerville C, Harris BD, LaPan M, Atwal GS, Barnes BJ.
Carter JA, et al. Among authors: lapan m.
J Immunother Cancer. 2023 Dec 22;11(12):e007935. doi: 10.1136/jitc-2023-007935.
J Immunother Cancer. 2023.
PMID: 38135347
Free PMC article.
Item in Clipboard
Loss of IRF5 increases ribosome biogenesis leading to alterations in mammary gland architecture and metastasis.
Brune Z, Li D, Song S, Li DI, Castro I, Rasquinha R, Rice MR, Guo Q, Kampta K, Moss M, Lallo M, Pimenta E, Somerville C, Lapan M, Nelson V, Dos Santos CO, Blanc L, Pruitt K, Barnes BJ.
Brune Z, et al. Among authors: lapan m.
bioRxiv [Preprint]. 2023 May 1:2023.05.01.538998. doi: 10.1101/2023.05.01.538998.
bioRxiv. 2023.
PMID: 37292919
Free PMC article.
Preprint.
Item in Clipboard
Identification of pan-cancer/testis genes and validation of therapeutic targeting in triple-negative breast cancer: Lin28a- and Siglece-based vaccination induces anti-tumor immunity and inhibits metastasis.
Carter JA, Matta B, Battaglia J, Somerville C, Harris BD, LaPan M, Atwal GS, Barnes BJ.
Carter JA, et al. Among authors: lapan m.
bioRxiv [Preprint]. 2023 May 10:2023.05.09.539617. doi: 10.1101/2023.05.09.539617.
bioRxiv. 2023.
PMID: 37214884
Free PMC article.
Updated.
Preprint.
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Decubitus ulcers: update on new approaches to treatment.
Mulder GD, LaPan M.
Mulder GD, et al. Among authors: lapan m.
Geriatrics. 1988 Sep;43(9):37-9, 44-5, 49-50.
Geriatrics. 1988.
PMID: 3261704
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