Krueger K - Search Results

1

Efficacy and Safety of Continued Treatment With Mirikizumab in a Phase 2 Trial of Patients With Ulcerative Colitis.

Sandborn WJ, Ferrante M, Bhandari BR, Berliba E, Hibi T, D'Haens GR, Tuttle JL, Krueger K, Friedrich S, Durante M, Arora V, Naegeli AN, Schmitz J, Feagan BG. Sandborn WJ, et al. Among authors: krueger k. Clin Gastroenterol Hepatol. 2022 Jan;20(1):105-115.e14. doi: 10.1016/j.cgh.2020.09.028. Epub 2020 Sep 18. Clin Gastroenterol Hepatol. 2022. PMID: 32950748 Free article. Clinical Trial.

2

Evacetrapib at a supratherapeutic steady state concentration does not prolong QT in a thorough QT/QTc study in healthy participants.

Suico JG, Friedrich S, Krueger KA, Zhang W. Suico JG, et al. J Cardiovasc Pharmacol Ther. 2014 May;19(3):283-9. doi: 10.1177/1074248413510784. Epub 2013 Nov 22. J Cardiovasc Pharmacol Ther. 2014. PMID: 24271137 Clinical Trial.

3

Effects of the cholesteryl ester transfer protein inhibitor evacetrapib on lipoproteins, apolipoproteins and 24-h ambulatory blood pressure in healthy adults.

Suico JG, Wang MD, Friedrich S, Cannady EA, Konkoy CS, Ruotolo G, Krueger KA. Suico JG, et al. J Pharm Pharmacol. 2014 Nov;66(11):1576-85. doi: 10.1111/jphp.12287. Epub 2014 Jun 24. J Pharm Pharmacol. 2014. PMID: 24961753 Free PMC article. Clinical Trial.

4

CYP-mediated drug-drug interactions with evacetrapib, an investigational CETP inhibitor: in vitro prediction and clinical outcome.

Cannady EA, Suico JG, Wang MD, Friedrich S, Rehmel JR, Nicholls SJ, Krueger KA. Cannady EA, et al. Br J Clin Pharmacol. 2015 Dec;80(6):1388-98. doi: 10.1111/bcp.12730. Epub 2015 Oct 27. Br J Clin Pharmacol. 2015. PMID: 26264702 Free PMC article. Clinical Trial.

5

The pharmacokinetics and pharmacokinetic/pharmacodynamic relationships of evacetrapib administered as monotherapy or in combination with statins.

Friedrich S, Kastelein JJ, James D, Waterhouse T, Nissen SE, Nicholls SJ, Krueger KA. Friedrich S, et al. Among authors: krueger ka. CPT Pharmacometrics Syst Pharmacol. 2014 Jan 22;3(1):e94. doi: 10.1038/psp.2013.70. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 24452615 Free PMC article.

6

Safety and efficacy of LY3015014, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9): a randomized, placebo-controlled Phase 2 study.

Kastelein JJ, Nissen SE, Rader DJ, Hovingh GK, Wang MD, Shen T, Krueger KA. Kastelein JJ, et al. Eur Heart J. 2016 May 1;37(17):1360-9. doi: 10.1093/eurheartj/ehv707. Epub 2016 Jan 12. Eur Heart J. 2016. PMID: 26757788 Free PMC article. Clinical Trial.

7

Efficacy, safety, tolerability, and pharmacokinetic profile of evacetrapib administered as monotherapy or in combination with atorvastatin in Japanese patients with dyslipidemia.

Teramoto T, Takeuchi M, Morisaki Y, Ruotolo G, Krueger KA. Teramoto T, et al. Am J Cardiol. 2014 Jun 15;113(12):2021-9. doi: 10.1016/j.amjcard.2014.03.045. Epub 2014 Apr 2. Am J Cardiol. 2014. PMID: 24786356 Free article. Clinical Trial.

8

Post hoc analysis of data from the Multiple Outcomes of Raloxifene Evaluation (MORE) trial on the effects of three years of raloxifene treatment on glycemic control and cardiovascular disease risk factors in women with and without type 2 diabetes.

Barrett-Connor E, Ensrud KE, Harper K, Mason TM, Sashegyi A, Krueger KA, Anderson PW. Barrett-Connor E, et al. Among authors: krueger ka. Clin Ther. 2003 Mar;25(3):919-30. doi: 10.1016/s0149-2918(03)80114-5. Clin Ther. 2003. PMID: 12852708 Clinical Trial.

9

Population Pharmacokinetics (PK) and Pharmacodynamics (PD) Analysis of LY3015014, a Monoclonal Antibody to Protein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Healthy Subjects and Hypercholesterolemia Patients.

Shen T, James DE, Krueger KA. Shen T, et al. Pharm Res. 2017 Jan;34(1):185-192. doi: 10.1007/s11095-016-2054-6. Epub 2016 Nov 7. Pharm Res. 2017. PMID: 27822850 Clinical Trial.

10

Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib.

Nicholls SJ, Ruotolo G, Brewer HB, Kane JP, Wang MD, Krueger KA, Adelman SJ, Nissen SE, Rader DJ. Nicholls SJ, et al. J Am Coll Cardiol. 2015 Nov 17;66(20):2201-2210. doi: 10.1016/j.jacc.2015.09.013. J Am Coll Cardiol. 2015. PMID: 26564598 Free article. Clinical Trial.

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