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Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity.
van Hasselt JGC, Rahman R, Hansen J, Stern A, Shim JV, Xiong Y, Pickard A, Jayaraman G, Hu B, Mahajan M, Gallo JM, Goldfarb J, Sobie EA, Birtwistle MR, Schlessinger A, Azeloglu EU, Iyengar R. van Hasselt JGC, et al. Among authors: birtwistle mr. Nat Commun. 2020 Sep 23;11(1):4809. doi: 10.1038/s41467-020-18396-7. Nat Commun. 2020. PMID: 32968055 Free PMC article.
Mechanistic vs. Empirical network models of drug action.
Birtwistle MR, Mager DE, Gallo JM. Birtwistle MR, et al. CPT Pharmacometrics Syst Pharmacol. 2013 Sep 6;2(9):e72. doi: 10.1038/psp.2013.51. CPT Pharmacometrics Syst Pharmacol. 2013. PMID: 24448020 Free PMC article.
Network pharmacodynamic models for customized cancer therapy.
Gallo JM, Birtwistle MR. Gallo JM, et al. Among authors: birtwistle mr. Wiley Interdiscip Rev Syst Biol Med. 2015 Jul-Aug;7(4):243-51. doi: 10.1002/wsbm.1300. Epub 2015 Apr 24. Wiley Interdiscip Rev Syst Biol Med. 2015. PMID: 25914386 Free PMC article.
Cell size assays for mass cytometry.
Stern AD, Rahman AH, Birtwistle MR. Stern AD, et al. Among authors: birtwistle mr. Cytometry A. 2017 Jan;91(1):14-24. doi: 10.1002/cyto.a.23000. Epub 2016 Oct 21. Cytometry A. 2017. PMID: 27768827 Free PMC article.
Drug response consistency in CCLE and CGP.
Bouhaddou M, DiStefano MS, Riesel EA, Carrasco E, Holzapfel HY, Jones DC, Smith GR, Stern AD, Somani SS, Thompson TV, Birtwistle MR. Bouhaddou M, et al. Among authors: birtwistle mr. Nature. 2016 Nov 30;540(7631):E9-E10. doi: 10.1038/nature20580. Nature. 2016. PMID: 27905419 Free PMC article. No abstract available.
A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries.
Xiong Y, Soumillon M, Wu J, Hansen J, Hu B, van Hasselt JGC, Jayaraman G, Lim R, Bouhaddou M, Ornelas L, Bochicchio J, Lenaeus L, Stocksdale J, Shim J, Gomez E, Sareen D, Svendsen C, Thompson LM, Mahajan M, Iyengar R, Sobie EA, Azeloglu EU, Birtwistle MR. Xiong Y, et al. Among authors: birtwistle mr. Sci Rep. 2017 Nov 7;7(1):14626. doi: 10.1038/s41598-017-14892-x. Sci Rep. 2017. PMID: 29116112 Free PMC article.
The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.
Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, Forlin M, Koleti A, Vidovic D, Chung C, Schürer SC, Vasiliauskas J, Pilarczyk M, Shamsaei B, Fazel M, Ren Y, Niu W, Clark NA, White S, Mahi N, Zhang L, Kouril M, Reichard JF, Sivaganesan S, Medvedovic M, Meller J, Koch RJ, Birtwistle MR, Iyengar R, Sobie EA, Azeloglu EU, Kaye J, Osterloh J, Haston K, Kalra J, Finkbiener S, Li J, Milani P, Adam M, Escalante-Chong R, Sachs K, Lenail A, Ramamoorthy D, Fraenkel E, Daigle G, Hussain U, Coye A, Rothstein J, Sareen D, Ornelas L, Banuelos M, Mandefro B, Ho R, Svendsen CN, Lim RG, Stocksdale J, Casale MS, Thompson TG, Wu J, Thompson LM, Dardov V, Venkatraman V, Matlock A, Van Eyk JE, Jaffe JD, Papanastasiou M, Subramanian A, Golub TR, Erickson SD, Fallahi-Sichani M, Hafner M, Gray NS, Lin JR, Mills CE, Muhlich JL, Niepel M, Shamu CE, Williams EH, Wrobel D, Sorger PK, Heiser LM, Gray JW, Korkola JE, Mills GB, LaBarge M, Feiler HS, Dane MA, Bucher E, Nederlof M, Sudar D, Gross S, Kilburn DF, Smith R, Devlin K, Margolis R, Derr L, Lee A, Pillai A. Keenan AB, et al. Among authors: birtwistle mr. Cell Syst. 2018 Jan 24;6(1):13-24. doi: 10.1016/j.cels.2017.11.001. Epub 2017 Nov 29. Cell Syst. 2018. PMID: 29199020 Free PMC article. Review.
A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens.
Bouhaddou M, Barrette AM, Stern AD, Koch RJ, DiStefano MS, Riesel EA, Santos LC, Tan AL, Mertz AE, Birtwistle MR. Bouhaddou M, et al. Among authors: birtwistle mr. PLoS Comput Biol. 2018 Mar 26;14(3):e1005985. doi: 10.1371/journal.pcbi.1005985. eCollection 2018 Mar. PLoS Comput Biol. 2018. PMID: 29579036 Free PMC article.
75 results