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Periphilin self-association underpins epigenetic silencing by the HUSH complex.
Prigozhin DM, Douse CH, Farleigh LE, Albecka A, Tchasovnikarova IA, Timms RT, Oda SI, Adolf F, Freund SMV, Maslen S, Lehner PJ, Modis Y. Prigozhin DM, et al. Among authors: freund smv. Nucleic Acids Res. 2020 Oct 9;48(18):10313-10328. doi: 10.1093/nar/gkaa785. Nucleic Acids Res. 2020. PMID: 32976585 Free PMC article.
Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Mevissen TET, Kulathu Y, Mulder MPC, Geurink PP, Maslen SL, Gersch M, Elliott PR, Burke JE, van Tol BDM, Akutsu M, Oualid FE, Kawasaki M, Freund SMV, Ovaa H, Komander D. Mevissen TET, et al. Among authors: freund smv. Nature. 2016 Oct 20;538(7625):402-405. doi: 10.1038/nature19836. Epub 2016 Oct 12. Nature. 2016. PMID: 27732584 Free PMC article.
Structure of PINK1 in complex with its substrate ubiquitin.
Schubert AF, Gladkova C, Pardon E, Wagstaff JL, Freund SMV, Steyaert J, Maslen SL, Komander D. Schubert AF, et al. Among authors: freund smv. Nature. 2017 Dec 7;552(7683):51-56. doi: 10.1038/nature24645. Epub 2017 Oct 30. Nature. 2017. PMID: 29160309 Free PMC article.
Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation.
Biggs GS, Klein OJ, Maslen SL, Skehel JM, Rutherford TJ, Freund SMV, Hollfelder F, Boss SR, Barker PD. Biggs GS, et al. Among authors: freund smv. Angew Chem Int Ed Engl. 2021 May 3;60(19):10919-10927. doi: 10.1002/anie.202015834. Epub 2021 Mar 26. Angew Chem Int Ed Engl. 2021. PMID: 33616271 Free PMC article.
135 results