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A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Kreye J, Reincke SM, Kornau HC, Sánchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Höltje M, Dietert K, Stöffler L, von Wardenburg N, van Hoof S, Homeyer MA, Hoffmann J, Abdelgawad A, Gruber AD, Bertzbach LD, Vladimirova D, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Müller MA, Drosten C, Wendisch D, Sander LE, Osterrieder N, Wilson IA, Prüss H. Kreye J, et al. Cell. 2020 Nov 12;183(4):1058-1069.e19. doi: 10.1016/j.cell.2020.09.049. Epub 2020 Sep 23. Cell. 2020. PMID: 33058755 Free PMC article.
Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.
Kreye J, Wenke NK, Chayka M, Leubner J, Murugan R, Maier N, Jurek B, Ly LT, Brandl D, Rost BR, Stumpf A, Schulz P, Radbruch H, Hauser AE, Pache F, Meisel A, Harms L, Paul F, Dirnagl U, Garner C, Schmitz D, Wardemann H, Prüss H. Kreye J, et al. Brain. 2016 Oct;139(Pt 10):2641-2652. doi: 10.1093/brain/aww208. Epub 2016 Aug 20. Brain. 2016. PMID: 27543972
N-methyl-D-aspartate receptor dysfunction by unmutated human antibodies against the NR1 subunit.
Wenke NK, Kreye J, Andrzejak E, van Casteren A, Leubner J, Murgueitio MS, Reincke SM, Secker C, Schmidl L, Geis C, Ackermann F, Nikolaus M, Garner CC, Wardemann H, Wolber G, Prüss H. Wenke NK, et al. Among authors: kreye j. Ann Neurol. 2019 May;85(5):771-776. doi: 10.1002/ana.25460. Epub 2019 Apr 2. Ann Neurol. 2019. PMID: 30843274 Free PMC article.
Human gestational N-methyl-d-aspartate receptor autoantibodies impair neonatal murine brain function.
Jurek B, Chayka M, Kreye J, Lang K, Kraus L, Fidzinski P, Kornau HC, Dao LM, Wenke NK, Long M, Rivalan M, Winter Y, Leubner J, Herken J, Mayer S, Mueller S, Boehm-Sturm P, Dirnagl U, Schmitz D, Kölch M, Prüss H. Jurek B, et al. Among authors: kreye j. Ann Neurol. 2019 Nov;86(5):656-670. doi: 10.1002/ana.25552. Epub 2019 Sep 18. Ann Neurol. 2019. PMID: 31325344
IgA autoantibodies against native myelin basic protein in a patient with MS.
Schumacher H, Wenke NK, Kreye J, Höltje M, Marcus K, May C, Prüss H. Schumacher H, et al. Among authors: kreye j. Neurol Neuroimmunol Neuroinflamm. 2019 May 1;6(4):e569. doi: 10.1212/NXI.0000000000000569. eCollection 2019 Jul. Neurol Neuroimmunol Neuroinflamm. 2019. PMID: 31355305 Free PMC article. No abstract available.
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