McLaughlin M - Search Results

1

Multiplex enCas12a screens detect functional buffering among paralogs otherwise masked in monogenic Cas9 knockout screens.

Dede M, McLaughlin M, Kim E, Hart T. Dede M, et al. Among authors: mclaughlin m. Genome Biol. 2020 Oct 15;21(1):262. doi: 10.1186/s13059-020-02173-2. Genome Biol. 2020. PMID: 33059726 Free PMC article.

2

A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations.

Nixon AML, Duque A, Yelle N, McLaughlin M, Davoudi S, Pedley NM, Haynes J, Brown KR, Pan J, Hart T, Gilbert PM, Singh SK, O'Brien CA, Sidhu SS, Moffat J. Nixon AML, et al. Among authors: mclaughlin m. Sci Rep. 2019 Jan 29;9(1):842. doi: 10.1038/s41598-018-37462-1. Sci Rep. 2019. PMID: 30696911 Free PMC article.

3

Identifying chemogenetic interactions from CRISPR screens with drugZ.

Colic M, Wang G, Zimmermann M, Mascall K, McLaughlin M, Bertolet L, Lenoir WF, Moffat J, Angers S, Durocher D, Hart T. Colic M, et al. Among authors: mclaughlin m. Genome Med. 2019 Aug 22;11(1):52. doi: 10.1186/s13073-019-0665-3. Genome Med. 2019. PMID: 31439014 Free PMC article.

4

C17orf53 is identified as a novel gene involved in inter-strand crosslink repair.

Wang C, Chen Z, Su D, Tang M, Nie L, Zhang H, Feng X, Wang R, Shen X, Srivastava M, McLaughlin ME, Hart T, Li L, Chen J. Wang C, et al. Among authors: mclaughlin me. DNA Repair (Amst). 2020 Nov;95:102946. doi: 10.1016/j.dnarep.2020.102946. Epub 2020 Aug 15. DNA Repair (Amst). 2020. PMID: 32853826 Free PMC article.

5

DNA polymerase ι compensates for Fanconi anemia pathway deficiency by countering DNA replication stress.

Wang R, Lenoir WF, Wang C, Su D, McLaughlin M, Hu Q, Shen X, Tian Y, Klages-Mundt N, Lynn E, Wood RD, Chen J, Hart T, Li L. Wang R, et al. Among authors: mclaughlin m. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33436-33445. doi: 10.1073/pnas.2008821117. Epub 2020 Dec 21. Proc Natl Acad Sci U S A. 2020. PMID: 33376220 Free PMC article.

6

Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells.

Lenoir WF, Morgado M, DeWeirdt PC, McLaughlin M, Griffith AL, Sangree AK, Feeley MN, Esmaeili Anvar N, Kim E, Bertolet LL, Colic M, Dede M, Doench JG, Hart T. Lenoir WF, et al. Among authors: mclaughlin m. Nat Commun. 2021 Nov 11;12(1):6506. doi: 10.1038/s41467-021-26867-8. Nat Commun. 2021. PMID: 34764293 Free PMC article.

7

Genome-wide CRISPR-Cas9 screen analyzed by SLIDER identifies network of repressor complexes that regulate TRIM24.

Patel LR, Stratton SA, McLaughlin M, Krause P, Allton K, Rivas AL, Barbosa D, Hart T, Barton MC. Patel LR, et al. Among authors: mclaughlin m. iScience. 2023 Jun 14;26(7):107126. doi: 10.1016/j.isci.2023.107126. eCollection 2023 Jul 21. iScience. 2023. PMID: 37426340 Free PMC article.

8

Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition.

Wang C, Wang G, Feng X, Shepherd P, Zhang J, Tang M, Chen Z, Srivastava M, McLaughlin ME, Navone NM, Hart GT, Chen J. Wang C, et al. Among authors: mclaughlin me. Oncogene. 2019 Apr;38(14):2451-2463. doi: 10.1038/s41388-018-0606-4. Epub 2018 Dec 7. Oncogene. 2019. PMID: 30532030 Free PMC article.

9

SARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials.

Fisher LH, Kee JJ, Liu A, Espinosa CM, Randhawa AK, Ludwig J, Magaret CA, Robinson ST, Gilbert PB, Hyrien O, Kublin JG, Rouphael N, Falsey AR, Sobieszczyk ME, El Sahly HM, Grinsztejn B, Gray GE, Kotloff KL, Gay CL, Leav B, Hirsch I, Struyf F, Dunkle LM, Neuzil KM, Corey L, Huang Y, Goepfert PA, Walsh SR, Baden LR, Janes H; COVID-19 Prevention Network (CoVPN). Fisher LH, et al. JAMA Netw Open. 2024 May 1;7(5):e2412835. doi: 10.1001/jamanetworkopen.2024.12835. JAMA Netw Open. 2024. PMID: 38780941 Free PMC article.

10

Measuring the impact of dietary supplementation with citrus or cucumber extract on chicken gut microbiota using 16s rRNA gene sequencing.

Riva F, McGuinness DH, McKeegan DEF, Peinado-Izaguerri J, Bruggeman G, Hermans D, Eckersall PD, McLaughlin M, Bain M. Riva F, et al. Among authors: mclaughlin m. Vet Res Commun. 2024 May 23. doi: 10.1007/s11259-024-10417-w. Online ahead of print. Vet Res Commun. 2024. PMID: 38780824

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