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Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance.
Gauttier V, Pengam S, Durand J, Biteau K, Mary C, Morello A, Néel M, Porto G, Teppaz G, Thepenier V, Danger R, Vince N, Wilhelm E, Girault I, Abes R, Ruiz C, Trilleaud C, Ralph K, Trombetta ES, Garcia A, Vignard V, Martinet B, Glémain A, Bruneau S, Haspot F, Dehmani S, Duplouye P, Miyasaka M, Labarrière N, Laplaud D, Le Bas-Bernardet S, Blanquart C, Catros V, Gouraud PA, Archambeaud I, Aublé H, Metairie S, Mosnier JF, Costantini D, Blancho G, Conchon S, Vanhove B, Poirier N. Gauttier V, et al. Among authors: garcia a. J Clin Invest. 2020 Nov 2;130(11):6109-6123. doi: 10.1172/JCI135528. J Clin Invest. 2020. PMID: 33074246 Free PMC article.
IL-15 Harnesses Pro-inflammatory Function of TEMRA CD8 in Kidney-Transplant Recipients.
Tilly G, Doan-Ngoc TM, Yap M, Caristan A, Jacquemont L, Danger R, Cadoux M, Bruneau S, Giral M, Guerif P, Nicol B, Garcia A, Laplaud DA, Brouard S, Pecqueur Hellman C, Degauque N. Tilly G, et al. Among authors: garcia a. Front Immunol. 2017 Jun 30;8:778. doi: 10.3389/fimmu.2017.00778. eCollection 2017. Front Immunol. 2017. PMID: 28713392 Free PMC article.
Integrative molecular profiling of autoreactive CD4 T cells in autoimmune hepatitis.
Renand A, Cervera-Marzal I, Gil L, Dong C, Garcia A, Kervagoret E, Aublé H, Habes S, Chevalier C, Vavasseur F, Clémenceau B, Cardon A, Judor JP, Mosnier JF, Tanné F, Laplaud DA, Brouard S, Gournay J, Milpied P, Conchon S. Renand A, et al. Among authors: garcia a. J Hepatol. 2020 Dec;73(6):1379-1390. doi: 10.1016/j.jhep.2020.05.053. Epub 2020 Jul 8. J Hepatol. 2020. PMID: 32649971
Effector Memory-Expressing CD45RA (TEMRA) CD8+ T Cells from Kidney Transplant Recipients Exhibit Enhanced Purinergic P2X4 Receptor-Dependent Proinflammatory and Migratory Responses.
Doan Ngoc TM, Tilly G, Danger R, Bonizec O, Masset C, Guérif P, Bruneau S, Glemain A, Harb J, Cadoux M, Vivet A, Mai HL, Garcia A, Laplaud D, Liblau R, Giral M, Blandin S, Feyeux M, Dubreuil L, Pecqueur C, Cyr M, Ni W, Brouard S, Degauque N; on behalf on the DIVAT Consortium; DIVAT Consortium. Doan Ngoc TM, et al. Among authors: garcia a. J Am Soc Nephrol. 2022 Dec;33(12):2211-2231. doi: 10.1681/ASN.2022030286. Epub 2022 Oct 24. J Am Soc Nephrol. 2022. PMID: 36280286 Free PMC article.
Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis.
Salou M, Garcia A, Michel L, Gainche-Salmon A, Loussouarn D, Nicol B, Guillot F, Hulin P, Nedellec S, Baron D, Ramstein G, Soulillou JP, Brouard S, Nicot AB, Degauque N, Laplaud DA. Salou M, et al. Among authors: garcia a. Ann Clin Transl Neurol. 2015 Jun;2(6):609-22. doi: 10.1002/acn3.199. Epub 2015 Apr 28. Ann Clin Transl Neurol. 2015. PMID: 26125037 Free PMC article.
Patients With Severe Multiple Sclerosis Exhibit Functionally Altered CD8+ Regulatory T Cells.
Benallegue N, Nicol B, Lasselin J, Bézie S, Flippe L, Regue H, Vimond N, Remy S, Garcia A, Le Frère F, Anegon I, Laplaud D, Guillonneau C. Benallegue N, et al. Among authors: garcia a. Neurol Neuroimmunol Neuroinflamm. 2022 Oct 20;9(6):e200016. doi: 10.1212/NXI.0000000000200016. Print 2022 Nov. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 36266052 Free PMC article.
Immune Profiling Reveals the T-Cell Effect of Ocrelizumab in Early Relapsing-Remitting Multiple Sclerosis.
Garcia A, Dugast E, Shah S, Morille J, Lebrun-Frenay C, Thouvenot E, De Sèze J, Le Page E, Vukusic S, Maurousset A, Berger E, Casez O, Labauge P, Ruet A, Raposo C, Bakdache F, Buffels R, Le Frère F, Nicot A, Wiertlewski S, Gourraud PA, Berthelot L, Laplaud D. Garcia A, et al. Neurol Neuroimmunol Neuroinflamm. 2023 Feb 21;10(3):e200091. doi: 10.1212/NXI.0000000000200091. Print 2023 May. Neurol Neuroimmunol Neuroinflamm. 2023. PMID: 36810163 Free PMC article.
8,247 results