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Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Xu D, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S. Han Y, et al. Among authors: johnson jl. Nature. 2021 Jan;589(7841):270-275. doi: 10.1038/s41586-020-2901-9. Epub 2020 Oct 28. Nature. 2021. PMID: 33116299 Free PMC article.
A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification.
Browne CM, Jiang B, Ficarro SB, Doctor ZM, Johnson JL, Card JD, Sivakumaren SC, Alexander WM, Yaron TM, Murphy CJ, Kwiatkowski NP, Zhang T, Cantley LC, Gray NS, Marto JA. Browne CM, et al. Among authors: johnson jl. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20. J Am Chem Soc. 2019. PMID: 30518210 Free PMC article.
Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity.
Ferguson FM, Doctor ZM, Ficarro SB, Browne CM, Marto JA, Johnson JL, Yaron TM, Cantley LC, Kim ND, Sim T, Berberich MJ, Kalocsay M, Sorger PK, Gray NS. Ferguson FM, et al. Among authors: johnson jl. Cell Chem Biol. 2019 Jun 20;26(6):804-817.e12. doi: 10.1016/j.chembiol.2019.02.015. Epub 2019 Mar 28. Cell Chem Biol. 2019. PMID: 30930164 Free PMC article.
Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1).
Balasuriya N, Davey NE, Johnson JL, Liu H, Biggar KK, Cantley LC, Li SS, O'Donoghue P. Balasuriya N, et al. Among authors: johnson jl. J Biol Chem. 2020 Jun 12;295(24):8120-8134. doi: 10.1074/jbc.RA119.012425. Epub 2020 Apr 29. J Biol Chem. 2020. PMID: 32350110 Free PMC article.
Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids.
Han Y, Yang L, Duan X, Duan F, Nilsson-Payant BE, Yaron TM, Wang P, Tang X, Zhang T, Zhao Z, Bram Y, Redmond D, Houghton S, Nguyen D, Xu D, Wang X, Uhl S, Huang Y, Johnson JL, Xiang J, Wang H, Pan FC, Cantley LC, tenOever BR, Ho DD, Evans T, Schwartz RE, Chen HJ, Chen S. Han Y, et al. Among authors: johnson jl. bioRxiv [Preprint]. 2020 May 5:2020.05.05.079095. doi: 10.1101/2020.05.05.079095. bioRxiv. 2020. PMID: 32511403 Free PMC article. Preprint.
1,677 results