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Multielectrode Arrays.
Methods Mol Biol. 2021;2188:109-132. doi: 10.1007/978-1-0716-0818-0_6.
Methods Mol Biol. 2021.
PMID: 33119849
Discovery of CVN417, a Novel Brain-Penetrant α6-Containing Nicotinic Receptor Antagonist for the Modulation of Motor Dysfunction.
Christie LA, Brice NL, Rowland A, Dickson L, Anand R, Teall M, Doyle KJ, Narayana L, Mitchell C, Harvey JRM, Mulligan V, Dawson LA, Cragg SJ, Carlton M, Bürli RW.
Christie LA, et al. Among authors: harvey jrm.
J Med Chem. 2023 Sep 14;66(17):11718-11731. doi: 10.1021/acs.jmedchem.3c00630. Epub 2023 Aug 31.
J Med Chem. 2023.
PMID: 37651656
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Discovery of CVN293, a Brain Permeable KCNK13 (THIK-1) Inhibitor Suitable for Clinical Assessment.
Bürli RW, Doyle KJ, Dickson L, Rowland A, Matthews K, Stott AJ, Teall M, Ossola B, Russell SG, Harvey JRM, Wu Y, Narayana L, Brice NL, Carlton M, Dawson LA.
Bürli RW, et al. Among authors: harvey jrm.
ACS Med Chem Lett. 2024 Apr 5;15(5):646-652. doi: 10.1021/acsmedchemlett.4c00035. eCollection 2024 May 9.
ACS Med Chem Lett. 2024.
PMID: 38746889
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Characterisation of C101248: A novel selective THIK-1 channel inhibitor for the modulation of microglial NLRP3-inflammasome.
Ossola B, Rifat A, Rowland A, Hunter H, Drinkall S, Bender C, Hamlischer M, Teall M, Burley R, Barker DF, Cadwalladr D, Dickson L, Lawrence JMK, Harvey JRM, Lizio M, Xu X, Kavanagh E, Cheung T, Sheardown S, Lawrence CB, Harte M, Brough D, Madry C, Matthews K, Doyle K, Page K, Powell J, Brice NL, Bürli RW, Carlton MB, Dawson LA.
Ossola B, et al. Among authors: harvey jrm.
Neuropharmacology. 2023 Feb 15;224:109330. doi: 10.1016/j.neuropharm.2022.109330. Epub 2022 Nov 12.
Neuropharmacology. 2023.
PMID: 36375694
Free PMC article.
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Tau isoform-specific enhancement of L-type calcium current and augmentation of afterhyperpolarization in rat hippocampal neurons.
Stan GF, Church TW, Randall E, Harvey JRM, Brown JT, Wilkinson KA, Hanley JG, Marrion NV.
Stan GF, et al. Among authors: harvey jrm.
Sci Rep. 2022 Sep 8;12(1):15231. doi: 10.1038/s41598-022-18648-0.
Sci Rep. 2022.
PMID: 36075936
Free PMC article.
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Ion Channels Controlling Circadian Rhythms in Suprachiasmatic Nucleus Excitability.
Harvey JRM, Plante AE, Meredith AL.
Harvey JRM, et al.
Physiol Rev. 2020 Oct 1;100(4):1415-1454. doi: 10.1152/physrev.00027.2019. Epub 2020 Mar 12.
Physiol Rev. 2020.
PMID: 32163720
Free PMC article.
Review.
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