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Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure.
Michalick L, Weidenfeld S, Grimmer B, Fatykhova D, Solymosi PD, Behrens F, Dohmen M, Brack MC, Schulz S, Thomasch E, Simmons S, Müller-Redetzky H, Suttorp N, Kurth F, Neudecker J, Toennies M, Bauer TT, Eggeling S, Corman VM, Hocke AC, Witzenrath M, Hippenstiel S, Kuebler WM. Michalick L, et al. Among authors: kuebler wm. Eur Respir J. 2021 Mar 11;57(3):2002384. doi: 10.1183/13993003.02384-2020. Print 2021 Mar. Eur Respir J. 2021. PMID: 33154030 Free PMC article.
Mast cells promote lung vascular remodelling in pulmonary hypertension.
Hoffmann J, Yin J, Kukucka M, Yin N, Saarikko I, Sterner-Kock A, Fujii H, Leong-Poi H, Kuppe H, Schermuly RT, Kuebler WM. Hoffmann J, et al. Among authors: kuebler wm. Eur Respir J. 2011 Jun;37(6):1400-10. doi: 10.1183/09031936.00043310. Epub 2010 Dec 9. Eur Respir J. 2011. PMID: 21148228 Free article.
Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6.
Samapati R, Yang Y, Yin J, Stoerger C, Arenz C, Dietrich A, Gudermann T, Adam D, Wu S, Freichel M, Flockerzi V, Uhlig S, Kuebler WM. Samapati R, et al. Among authors: kuebler wm. Am J Respir Crit Care Med. 2012 Jan 15;185(2):160-70. doi: 10.1164/rccm.201104-0717OC. Am J Respir Crit Care Med. 2012. PMID: 22246702
Novel regulators of endothelial barrier function.
Mehta D, Ravindran K, Kuebler WM. Mehta D, et al. Among authors: kuebler wm. Am J Physiol Lung Cell Mol Physiol. 2014 Dec 15;307(12):L924-35. doi: 10.1152/ajplung.00318.2014. Epub 2014 Nov 7. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 25381026 Free PMC article. Review.
CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction.
Tabeling C, Yu H, Wang L, Ranke H, Goldenberg NM, Zabini D, Noe E, Krauszman A, Gutbier B, Yin J, Schaefer M, Arenz C, Hocke AC, Suttorp N, Proia RL, Witzenrath M, Kuebler WM. Tabeling C, et al. Among authors: kuebler wm. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1614-23. doi: 10.1073/pnas.1421190112. Epub 2015 Mar 17. Proc Natl Acad Sci U S A. 2015. PMID: 25829545 Free PMC article.
Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury.
Yin J, Michalick L, Tang C, Tabuchi A, Goldenberg N, Dan Q, Awwad K, Wang L, Erfinanda L, Nouailles G, Witzenrath M, Vogelzang A, Lv L, Lee WL, Zhang H, Rotstein O, Kapus A, Szaszi K, Fleming I, Liedtke WB, Kuppe H, Kuebler WM. Yin J, et al. Among authors: kuebler wm. Am J Respir Cell Mol Biol. 2016 Mar;54(3):370-83. doi: 10.1165/rcmb.2014-0225OC. Am J Respir Cell Mol Biol. 2016. PMID: 26222277
Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2-induced airway inflammation and remodeling.
Tabeling C, Herbert J, Hocke AC, Lamb DJ, Wollin SL, Erb KJ, Boiarina E, Movassagh H, Scheffel J, Doehn JM, Hippenstiel S, Maurer M, Gounni AS, Kuebler WM, Suttorp N, Witzenrath M. Tabeling C, et al. Among authors: kuebler wm. Allergy. 2017 Jul;72(7):1061-1072. doi: 10.1111/all.13101. Epub 2017 Jan 12. Allergy. 2017. PMID: 27906453
The endothelium in hypoxic pulmonary vasoconstriction.
Grimmer B, Kuebler WM. Grimmer B, et al. Among authors: kuebler wm. J Appl Physiol (1985). 2017 Dec 1;123(6):1635-1646. doi: 10.1152/japplphysiol.00120.2017. Epub 2017 Aug 31. J Appl Physiol (1985). 2017. PMID: 28860164 Free article. Review.
315 results