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CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14.
Patterson BK, Seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari J, Pang APS, Sugai C, Mahyari E, Francisco EB, Pise A, Rodrigues H, Wu HL, Webb GM, Park BS, Kelly S, Pourhassan N, Lelic A, Kdouh L, Herrera M, Hall E, Bimber BN, Plassmeyer M, Gupta R, Alpan O, O'Halloran JA, Mudd PA, Akalin E, Ndhlovu LC, Sacha JB. Patterson BK, et al. Among authors: mudd pa. Int J Infect Dis. 2021 Feb;103:25-32. doi: 10.1016/j.ijid.2020.10.101. Epub 2020 Nov 10. Int J Infect Dis. 2021. PMID: 33186704 Free PMC article.
Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm.
Mudd PA, Crawford JC, Turner JS, Souquette A, Reynolds D, Bender D, Bosanquet JP, Anand NJ, Striker DA, Martin RS, Boon ACM, House SL, Remy KE, Hotchkiss RS, Presti RM, O'Halloran JA, Powderly WG, Thomas PG, Ellebedy AH. Mudd PA, et al. Sci Adv. 2020 Dec 9;6(50):eabe3024. doi: 10.1126/sciadv.abe3024. Print 2020 Dec. Sci Adv. 2020. PMID: 33187979 Free PMC article.
Circulating mitochondrial DNA is an early indicator of severe illness and mortality from COVID-19.
Scozzi D, Cano M, Ma L, Zhou D, Zhu JH, O'Halloran JA, Goss C, Rauseo AM, Liu Z, Sahu SK, Peritore V, Rocco M, Ricci A, Amodeo R, Aimati L, Ibrahim M, Hachem R, Kreisel D, Mudd PA, Kulkarni HS, Gelman AE. Scozzi D, et al. Among authors: mudd pa. JCI Insight. 2021 Feb 22;6(4):e143299. doi: 10.1172/jci.insight.143299. JCI Insight. 2021. PMID: 33444289 Free PMC article.
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19.
Corley MJ, Pang APS, Dody K, Mudd PA, Patterson BK, Seethamraju H, Bram Y, Peluso MJ, Torres L, Iyer NS, Premeaux TA, Yeung ST, Chandar V, Borczuk A, Schwartz RE, Henrich TJ, Deeks SG, Sacha JB, Ndhlovu LC. Corley MJ, et al. Among authors: mudd pa. J Leukoc Biol. 2021 Jul;110(1):21-26. doi: 10.1002/JLB.5HI0720-466R. Epub 2021 Jan 19. J Leukoc Biol. 2021. PMID: 33464637 Free PMC article.
Interleukin-6 Trajectory and Secondary Infections in Mechanically Ventilated Patients With Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Treated With Interleukin-6 Receptor Blocker.
Vazquez Guillamet MC, Kulkarni HS, Montes K, Samant M, Shaikh PA, Betthauser K, Mudd PA, Reynolds D, O'Halloran J, Lyons P, McEvoy C, Vazquez Guillamet R. Vazquez Guillamet MC, et al. Among authors: mudd pa. Crit Care Explor. 2021 Feb 3;3(2):e0343. doi: 10.1097/CCE.0000000000000343. eCollection 2021 Feb. Crit Care Explor. 2021. PMID: 33554125 Free PMC article.
Asthma in patients with suspected and diagnosed coronavirus disease 2019.
Cao L, Lee S, Krings JG, Rauseo AM, Reynolds D, Presti R, Goss C, Mudd PA, O'Halloran JA, Wang L. Cao L, et al. Among authors: mudd pa. Ann Allergy Asthma Immunol. 2021 May;126(5):535-541.e2. doi: 10.1016/j.anai.2021.02.020. Epub 2021 Feb 25. Ann Allergy Asthma Immunol. 2021. PMID: 33639262 Free PMC article.
Caspases and therapeutic potential of caspase inhibitors in moderate-severe SARS-CoV-2 infection and long COVID.
Plassmeyer M, Alpan O, Corley MJ, Premeaux TA, Lillard K, Coatney P, Vaziri T, Michalsky S, Pang APS, Bukhari Z, Yeung ST, Evering TH, Naughton G, Latterich M, Mudd P, Spada A, Rindone N, Loizou D, Ulrik Sønder S, Ndhlovu LC, Gupta R. Plassmeyer M, et al. Allergy. 2022 Jan;77(1):118-129. doi: 10.1111/all.14907. Epub 2021 Jun 2. Allergy. 2022. PMID: 33993490 Free PMC article.
73 results