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Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses.
Everts B, Perona-Wright G, Smits HH, Hokke CH, van der Ham AJ, Fitzsimmons CM, Doenhoff MJ, van der Bosch J, Mohrs K, Haas H, Mohrs M, Yazdanbakhsh M, Schramm G. Everts B, et al. Among authors: van der bosch j, van der ham aj. J Exp Med. 2009 Aug 3;206(8):1673-80. doi: 10.1084/jem.20082460. Epub 2009 Jul 27. J Exp Med. 2009. PMID: 19635864 Free PMC article.
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor.
Everts B, Hussaarts L, Driessen NN, Meevissen MH, Schramm G, van der Ham AJ, van der Hoeven B, Scholzen T, Burgdorf S, Mohrs M, Pearce EJ, Hokke CH, Haas H, Smits HH, Yazdanbakhsh M. Everts B, et al. Among authors: van der ham aj, van der hoeven b. J Exp Med. 2012 Sep 24;209(10):1753-67, S1. doi: 10.1084/jem.20111381. Epub 2012 Sep 10. J Exp Med. 2012. PMID: 22966004 Free PMC article.
Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.
Kaisar MMM, Ritter M, Del Fresno C, Jónasdóttir HS, van der Ham AJ, Pelgrom LR, Schramm G, Layland LE, Sancho D, Prazeres da Costa C, Giera M, Yazdanbakhsh M, Everts B. Kaisar MMM, et al. Among authors: van der ham aj. PLoS Biol. 2018 Apr 18;16(4):e2005504. doi: 10.1371/journal.pbio.2005504. eCollection 2018 Apr. PLoS Biol. 2018. PMID: 29668708 Free PMC article.
LKB1 expressed in dendritic cells governs the development and expansion of thymus-derived regulatory T cells.
Pelgrom LR, Patente TA, Sergushichev A, Esaulova E, Otto F, Ozir-Fazalalikhan A, van der Zande HJP, van der Ham AJ, van der Stel S, Artyomov MN, Everts B. Pelgrom LR, et al. Among authors: van der zande hjp, van der ham aj, van der stel s. Cell Res. 2019 May;29(5):406-419. doi: 10.1038/s41422-019-0161-8. Epub 2019 Apr 2. Cell Res. 2019. PMID: 30940876 Free PMC article.
29 results