Nichols TC - Search Results

1

A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells.

Nguyen GN, Everett JK, Kafle S, Roche AM, Raymond HE, Leiby J, Wood C, Assenmacher CA, Merricks EP, Long CT, Kazazian HH, Nichols TC, Bushman FD, Sabatino DE. Nguyen GN, et al. Among authors: nichols tc. Nat Biotechnol. 2021 Jan;39(1):47-55. doi: 10.1038/s41587-020-0741-7. Epub 2020 Nov 16. Nat Biotechnol. 2021. PMID: 33199875 Free PMC article.

2

The roles of von Willebrand factor and factor VIII in arterial thrombosis: studies in canine von Willebrand disease and hemophilia A.

Nichols TC, Bellinger DA, Reddick RL, Smith SV, Koch GG, Davis K, Sigman J, Brinkhous KM, Griggs TR, Read MS. Nichols TC, et al. Blood. 1993 May 15;81(10):2644-51. Blood. 1993. PMID: 8490173 Free article.

3

Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia.

Monahan PE, Samulski RJ, Tazelaar J, Xiao X, Nichols TC, Bellinger DA, Read MS, Walsh CE. Monahan PE, et al. Among authors: nichols tc. Gene Ther. 1998 Jan;5(1):40-9. doi: 10.1038/sj.gt.3300548. Gene Ther. 1998. PMID: 9536263

4

Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector.

Herzog RW, Yang EY, Couto LB, Hagstrom JN, Elwell D, Fields PA, Burton M, Bellinger DA, Read MS, Brinkhous KM, Podsakoff GM, Nichols TC, Kurtzman GJ, High KA. Herzog RW, et al. Among authors: nichols tc. Nat Med. 1999 Jan;5(1):56-63. doi: 10.1038/4743. Nat Med. 1999. PMID: 9883840

5

Persistent expression of canine factor IX in hemophilia B canines.

Chao H, Samulski R, Bellinger D, Monahan P, Nichols T, Walsh C. Chao H, et al. Gene Ther. 1999 Oct;6(10):1695-704. doi: 10.1038/sj.gt.3301024. Gene Ther. 1999. PMID: 10516718

6

Intracellular function in rehydrated lyophilized platelets.

Fischer TH, Merricks EP, Russell KE, Raymer RA, White GC, Bode AP, Nichols TC, Read MS. Fischer TH, et al. Among authors: nichols tc. Br J Haematol. 2000 Oct;111(1):167-74. doi: 10.1046/j.1365-2141.2000.02343.x. Br J Haematol. 2000. PMID: 11091197 Free article.

7

Lack of germline transmission of vector sequences following systemic administration of recombinant AAV-2 vector in males.

Arruda VR, Fields PA, Milner R, Wainwright L, De Miguel MP, Donovan PJ, Herzog RW, Nichols TC, Biegel JA, Razavi M, Dake M, Huff D, Flake AW, Couto L, Kay MA, High KA. Arruda VR, et al. Among authors: nichols tc. Mol Ther. 2001 Dec;4(6):586-92. doi: 10.1006/mthe.2001.0491. Mol Ther. 2001. PMID: 11735343 Free article.

8

Splenic clearance mechanisms of rehydrated, lyophilized platelets.

Fischer TH, Merricks E, Bellinger DA, Hayes PM, Smith RS, Raymer RA, Read MS, Nichols TC, Bode AP. Fischer TH, et al. Among authors: nichols tc. Artif Cells Blood Substit Immobil Biotechnol. 2001 Nov;29(6):439-51. doi: 10.1081/bio-100108549. Artif Cells Blood Substit Immobil Biotechnol. 2001. PMID: 11795630

9

Influence of vector dose on factor IX-specific T and B cell responses in muscle-directed gene therapy.

Herzog RW, Fields PA, Arruda VR, Brubaker JO, Armstrong E, McClintock D, Bellinger DA, Couto LB, Nichols TC, High KA. Herzog RW, et al. Among authors: nichols tc. Hum Gene Ther. 2002 Jul 20;13(11):1281-91. doi: 10.1089/104303402760128513. Hum Gene Ther. 2002. PMID: 12162811

10

Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury.

Pye J, Ardeshirpour F, McCain A, Bellinger DA, Merricks E, Adams J, Elliott PJ, Pien C, Fischer TH, Baldwin AS Jr, Nichols TC. Pye J, et al. Among authors: nichols tc. Am J Physiol Heart Circ Physiol. 2003 Mar;284(3):H919-26. doi: 10.1152/ajpheart.00851.2002. Epub 2002 Nov 7. Am J Physiol Heart Circ Physiol. 2003. PMID: 12424098 Free article.

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