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Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion.
Junqueira Alves C, Dariolli R, Haydak J, Kang S, Hannah T, Wiener RJ, DeFronzo S, Tejero R, Gusella GL, Ramakrishnan A, Alves Dias R, Wojcinski A, Kesari S, Shen L, Sobie EA, Rodrigues Furtado de Mendonça JP, Azeloglu EU, Zou H, Friedel RH. Junqueira Alves C, et al. Among authors: dariolli r. Nat Commun. 2021 Oct 14;12(1):6019. doi: 10.1038/s41467-021-26296-7. Nat Commun. 2021. PMID: 34650052 Free PMC article.
A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals.
Schaniel C, Dhanan P, Hu B, Xiong Y, Raghunandan T, Gonzalez DM, Dariolli R, D'Souza SL, Yadaw AS, Hansen J, Jayaraman G, Mathew B, Machado M, Berger SI, Tripodi J, Najfeld V, Garg J, Miller M, Surlyn CS, Michelis KC, Tangirala NC, Weerahandi H, Thomas DC, Beaumont KG, Sebra R, Mahajan M, Schadt E, Vidovic D, Schürer SC, Goldfarb J, Azeloglu EU, Birtwistle MR, Sobie EA, Kovacic JC, Dubois NC, Iyengar R. Schaniel C, et al. Among authors: dariolli r. Stem Cell Reports. 2021 Dec 14;16(12):3036-3049. doi: 10.1016/j.stemcr.2021.10.005. Epub 2021 Nov 4. Stem Cell Reports. 2021. PMID: 34739849 Free PMC article.
PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.
Wickramasinghe NM, Sachs D, Shewale B, Gonzalez DM, Dhanan-Krishnan P, Torre D, LaMarca E, Raimo S, Dariolli R, Serasinghe MN, Mayourian J, Sebra R, Beaumont K, Iyengar S, French DL, Hansen A, Eschenhagen T, Chipuk JE, Sobie EA, Jacobs A, Akbarian S, Ischiropoulos H, Ma'ayan A, Houten SM, Costa K, Dubois NC. Wickramasinghe NM, et al. Among authors: dariolli r. Cell Stem Cell. 2022 Apr 7;29(4):559-576.e7. doi: 10.1016/j.stem.2022.02.011. Epub 2022 Mar 23. Cell Stem Cell. 2022. PMID: 35325615 Free PMC article.
HRAS-Mutant Cardiomyocyte Model of Multifocal Atrial Tachycardia.
Rodríguez NA, Patel N, Dariolli R, Ng S, Aleman AG, Gong JQX, Lin HM, Rodríguez M, Josowitz R, Sol-Church K, Gripp KW, Lin X, Song SC, Fishman GI, Sobie EA, Gelb BD. Rodríguez NA, et al. Among authors: dariolli r. Circ Arrhythm Electrophysiol. 2024 Apr;17(4):e012022. doi: 10.1161/CIRCEP.123.012022. Epub 2024 Feb 28. Circ Arrhythm Electrophysiol. 2024. PMID: 38415356
Two heads are better than one: current landscape of integrating QSP and machine learning : An ISoP QSP SIG white paper by the working group on the integration of quantitative systems pharmacology and machine learning.
Zhang T, Androulakis IP, Bonate P, Cheng L, Helikar T, Parikh J, Rackauckas C, Subramanian K, Cho CR; Working Group. Zhang T, et al. J Pharmacokinet Pharmacodyn. 2022 Feb;49(1):5-18. doi: 10.1007/s10928-022-09805-z. Epub 2022 Feb 1. J Pharmacokinet Pharmacodyn. 2022. PMID: 35103884 Free PMC article. Review.
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