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Melanoma cells can be eliminated by sialylated CD43 × CD3 bispecific T cell engager formats in vitro and in vivo.
de Jong G, Bartels L, Kedde M, Verdegaal EME, Gillissen MA, Levie SE, Cercel MG, van Hal-van Veen SE, Fatmawati C, van de Berg D, Yasuda E, Claassen YB, Bakker AQ, van der Burg SH, Schotte R, Villaudy J, Spits H, Hazenberg MD, van Helden PM, Wagner K. de Jong G, et al. Among authors: schotte r. Cancer Immunol Immunother. 2021 Jun;70(6):1569-1581. doi: 10.1007/s00262-020-02780-9. Epub 2020 Nov 23. Cancer Immunol Immunother. 2021. PMID: 33225419 Free PMC article.
Tumor infiltrating lymphocytes (TIL) therapy in metastatic melanoma: boosting of neoantigen-specific T cell reactivity and long-term follow-up.
van den Berg JH, Heemskerk B, van Rooij N, Gomez-Eerland R, Michels S, van Zon M, de Boer R, Bakker NAM, Jorritsma-Smit A, van Buuren MM, Kvistborg P, Spits H, Schotte R, Mallo H, Karger M, van der Hage JA, Wouters MWJM, Pronk LM, Geukes Foppen MH, Blank CU, Beijnen JH, Nuijen B, Schumacher TN, Haanen JBAG. van den Berg JH, et al. Among authors: schotte r. J Immunother Cancer. 2020 Aug;8(2):e000848. doi: 10.1136/jitc-2020-000848. J Immunother Cancer. 2020. PMID: 32753545 Free PMC article. Clinical Trial.
Neoantigen landscape dynamics during human melanoma-T cell interactions.
Verdegaal EM, de Miranda NF, Visser M, Harryvan T, van Buuren MM, Andersen RS, Hadrup SR, van der Minne CE, Schotte R, Spits H, Haanen JB, Kapiteijn EH, Schumacher TN, van der Burg SH. Verdegaal EM, et al. Among authors: schotte r. Nature. 2016 Aug 4;536(7614):91-5. doi: 10.1038/nature18945. Epub 2016 Jun 27. Nature. 2016. PMID: 27350335
Developmental origin of pre-DC2.
Blom B, Ligthart SJ, Schotte R, Spits H. Blom B, et al. Among authors: schotte r. Hum Immunol. 2002 Dec;63(12):1072-80. doi: 10.1016/s0198-8859(02)00745-0. Hum Immunol. 2002. PMID: 12480250 Review.
Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.
Legrand N, Huntington ND, Nagasawa M, Bakker AQ, Schotte R, Strick-Marchand H, de Geus SJ, Pouw SM, Böhne M, Voordouw A, Weijer K, Di Santo JP, Spits H. Legrand N, et al. Among authors: schotte r. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13224-9. doi: 10.1073/pnas.1101398108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788504 Free PMC article.
21 results