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Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury.
Bailey AL, Kang LI, de Assis Barros D'Elia Zanella LGF, Silveira CGT, Ho YL, Foquet L, Bial G, McCune BT, Duarte-Neto AN, Thomas A, Raué HP, Byrnes K, Kallas EG, Slifka MK, Diamond MS. Bailey AL, et al. Among authors: bial g. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32648-32656. doi: 10.1073/pnas.2014096117. Epub 2020 Dec 2. Proc Natl Acad Sci U S A. 2020. PMID: 33268494 Free PMC article.
Brain integrity is altered by hepatic APOE ε4 in humanized-liver mice.
Giannisis A, Patra K, Edlund AK, Nieto LA, Benedicto-Gras J, Moussaud S, de la Rosa A, Twohig D, Bengtsson T, Fu Y, Bu G, Bial G, Foquet L, Hammarstedt C, Strom S, Kannisto K, Raber J, Ellis E, Nielsen HM. Giannisis A, et al. Among authors: bial g. Mol Psychiatry. 2022 Aug;27(8):3533-3543. doi: 10.1038/s41380-022-01548-0. Epub 2022 Apr 13. Mol Psychiatry. 2022. PMID: 35418601 Free PMC article.
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases.
Yarnall MTN, Ioannidi EI, Schmitt-Ulms C, Krajeski RN, Lim J, Villiger L, Zhou W, Jiang K, Garushyants SK, Roberts N, Zhang L, Vakulskas CA, Walker JA 2nd, Kadina AP, Zepeda AE, Holden K, Ma H, Xie J, Gao G, Foquet L, Bial G, Donnelly SK, Miyata Y, Radiloff DR, Henderson JM, Ujita A, Abudayyeh OO, Gootenberg JS. Yarnall MTN, et al. Among authors: bial g. Nat Biotechnol. 2023 Apr;41(4):500-512. doi: 10.1038/s41587-022-01527-4. Epub 2022 Nov 24. Nat Biotechnol. 2023. PMID: 36424489 Free PMC article.
Extensive double humanization of both liver and hematopoiesis in FRGN mice.
Wilson EM, Bial J, Tarlow B, Bial G, Jensen B, Greiner DL, Brehm MA, Grompe M. Wilson EM, et al. Among authors: bial g. Stem Cell Res. 2014 Nov;13(3 Pt A):404-12. doi: 10.1016/j.scr.2014.08.006. Epub 2014 Sep 6. Stem Cell Res. 2014. PMID: 25310256 Free PMC article.